ArticleObesity (Silver Spring, Md.)2015
Second-hand eating? Maternal perception of the food environment affects reproductive investment in mice.
Article in Obesity (Silver Spring, Md.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- No Significant Effect of Maternal Perception of the Food Environment on Reproductive Success or Pup Outcomes in C57BL/6J Mice.Obesity (Silver Spring, Md.) · 2018Article
- Validation of Body Condition Indices and Quantitative Magnetic Resonance in Estimating Body Composition in a Small Lizard.Journal of experimental zoology. Part A, Ecological genetics and physiology · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
objectiveLittle information exists on how perception of the food (or "energetic") environment affects body composition and reproductive investment. The hypothesis was tested that female mice, who are themselves consuming standard chow diets but who are exposed to conspecifics eating a rich "cafeteria diet," will exhibit altered weight gain and reproductive investment.
methodsFemale C57BL/6 mice were raised on a cafeteria diet. At maturity, subjects were switched to a standard chow diet, and their cage-mates were assigned to consume either a cafeteria diet (treatment, n = 20) or standard chow (control, n = 20). Subjects were mated and pups raised to weaning. Subjects and pups were analyzed for body composition.
resultsTreatment had no discernable effect on dam body weight or composition but caused pups to have lower body weight (P = 0.036) and less fat mass (P = 0.041). A nearly significant treatment effect on "time to successful reproduction" (avg. 55 versus 44 days), likely due to increased failed first pregnancies, (14/19 versus 8/19, P = 0.099) was found.
conclusionsThese data indicate that perceived food environment (independent of the diet actually consumed) can produce small pups with less body fat and possibly induce difficulties in pregnancy for dams. Replication and mechanistic studies should follow.
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Registered trials
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