Evidence map›Paper›PMID 25863718›Full record

Trial reportNeuron2015

Intrinsic and task-dependent coupling of neuronal population activity in human parietal cortex.

Brett L Foster, Vinitha Rangarajan, William R Shirer, Josef Parvizi

Open access · bronzeAbstract readClinical Trial
In one paragraph

Trial report in Neuron, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 100 papers.

0numbers the graph read from it
0cells of the map it votes in
100citing papers in PubMed
8.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

100 citing papers in PubMed, 196 citations in OpenAlex.

  1. Trial
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  4. Review
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  6. Quantum-inspired entanglement between collaborating brains during human memory encoding.Proceedings of the National Academy of Sciences of the United States of America · 2026
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  7. Article
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  10. Precise temporal dynamics of ripple events support order memory in human hippocampal-cortical circuits.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  11. Synchronous Rhythmic Activity in Area V4 Can Impair Shape Detection and Neuronal Reliability.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
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40 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Brett L FosterLaboratory of Behavioral & Cognitive Neurology, Stanford Human Intracranial Cognitive Electrophysiology Program (SHICEP), Department of Neurology & Neurological Sciences, School of Medicine, Stanford University, Stanford, CA 94305, USA. Electronic address: blfoster@stanford.edu.
Vinitha RangarajanLaboratory of Behavioral & Cognitive Neurology, Stanford Human Intracranial Cognitive Electrophysiology Program (SHICEP), Department of Neurology & Neurological Sciences, School of Medicine, Stanford University, Stanford, CA 94305, USA.
William R ShirerLaboratory of Behavioral & Cognitive Neurology, Stanford Human Intracranial Cognitive Electrophysiology Program (SHICEP), Department of Neurology & Neurological Sciences, School of Medicine, Stanford University, Stanford, CA 94305, USA.
Josef ParviziLaboratory of Behavioral & Cognitive Neurology, Stanford Human Intracranial Cognitive Electrophysiology Program (SHICEP), Department of Neurology & Neurological Sciences, School of Medicine, Stanford University, Stanford, CA 94305, USA.
Stanford University · USStanford Medicine · US

Funding

Memory, Attention, and Default Mode Processes in Human Posteromedial CortexR01NS078396 · NINDS · STANFORD UNIVERSITY · PI PARVIZI, JOSEF · 2012 to 2016
$1.7M
Spatiotemporal investigations of parietal cortex contributions to episodic memoryK99MH103479 · NIMH · STANFORD UNIVERSITY · PI FOSTER, BRETT · 2014 to 2015
$172k
NIMH NIH HHS K99 MH103479NIMH NIH HHS K99MH103479NINDS NIH HHS R01 NS078396NINDS NIH HHS R01NS078396
6 · The paper itself

Abstract

Human neuroimaging studies have suggested that subregions of the medial and lateral parietal cortex form key nodes of a larger brain network supporting episodic memory retrieval. To explore the electrophysiological correlates of functional connectivity between these subregions, we recorded simultaneously from medial and lateral parietal cortex using intracranial electrodes in three human subjects. We observed electrophysiological co-activation of retrosplenial/posterior cingulate cortex (RSC/PCC) and angular gyrus (AG) in the high-frequency broadband (HFB, or high-gamma) range, for conditions that required episodic retrieval. During resting and sleeping states, slow fluctuations (<1 Hz) of HFB activity were highly correlated between these task-co-activated neuronal populations. Furthermore, intrinsic electrophysiological connectivity patterns matched those obtained with resting-state fMRI from the same subjects. Our findings quantify the spatiotemporal dynamics of parietal cortex during episodic memory retrieval and provide clear neurophysiological correlates of intrinsic and task-dependent functional connectivity in the human brain.

Indexed as

AdultBrain MappingElectroencephalographyFemaleHuman ActivitiesHumansMagnetic Resonance ImagingMaleMemory, EpisodicNeuronsParietal LobeRestSleepTask Performance and AnalysisYoung Adult

Identifiers

PMID25863718
PMCPMC4409557
OpenAlexW2027320520

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.