ArticleThe Journal of pediatrics2015
Prenatal Second-Hand Smoke Exposure Measured with Urine Cotinine May Reduce Gross Motor Development at 18 Months of Age.
Article in The Journal of pediatrics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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Who cites it
17 citing papers in PubMed, 35 citations in OpenAlex.
- Indoor air pollution exposure and early childhood development in the Upstate KIDS Study.Environmental research · 2023Article
- Urinary nicotine metabolites are associated with cognitive impairment among the elderly in southern China.Tobacco induced diseases · 2023Article
- Early factors associated with risk of developmental coordination disorder in very preterm children: A prospective area-based cohort study in Italy.Paediatric and perinatal epidemiology · 2022Article
- Exposure of Mice to Thirdhand Smoke Modulates In Vitro and In Vivo Platelet Responses.International journal of molecular sciences · 2022Article
- Prenatal Exposure to Tobacco and Offspring Neurocognitive Development in the Healthy Start Study.The Journal of pediatrics · 2020Observational
- Exposure to prenatal secondhand smoke and early neurodevelopment: Mothers and Children's Environmental Health (MOCEH) study.Environmental health : a global access science source · 2019Article
- Investigating the Association Between Exposure to Second Hand SmokeFrontiers in pediatrics · 2019Article
- Critical developmental periods for effects of low-level tobacco smoke exposure on behavioral performance.Neurotoxicology · 2018Article
- Rates of exposure to environmental tobacco smoke from various indoor environments among US children and nonsmoker adolescents and adults.Environmental science and pollution research international · 2018Article
- Financial Incentives Alone Versus Incentivized Partner Support for Promoting Smoking Cessation During Pregnancy and Postpartum: Protocol for a Non-Randomized Single-Blinded Study.JMIR research protocols · 2017Article
- Sex-specific lung functional changes in adult mice exposed only to second-hand smoke in utero.Respiratory research · 2017Article
- Serious Psychological Distress and Smoking During Pregnancy in the United States: 2008-2014.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2017Article
- A Review of the Field on Children's Exposure to Environmental Contaminants: A Risk Assessment Approach.International journal of environmental research and public health · 2017Review
- Brief Counseling on Secondhand Smoke Exposure in Pregnant Women in Argentina and Uruguay.International journal of environmental research and public health · 2016Article
- Self-reported and laboratory evaluation of late pregnancy nicotine exposure and drugs of abuse.Journal of perinatology : official journal of the California Perinatal Association · 2016Article
- Cognitive and Behavioral Impairments Evoked by Low-Level Exposure to Tobacco Smoke Components: Comparison with Nicotine Alone.Toxicological sciences : an official journal of the Society of Toxicology · 2016Article
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Authors and funding
8 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate the association of second-hand smoke exposure of pregnant mothers using urine cotinine with the neurodevelopment of their children at 18 months of age in the mother-child cohort in Crete (Rhea Study). STUDY
designSelected participants were Greek mothers with singleton pregnancies, had never smoked, and had available urine cotinine measurements in pregnancy, and their children for whom a neurodevelopmental assessment was completed. We performed face-to-face interviews twice during pregnancy and postnatally, and assessed children's neurodevelopment at 18 months of age using the Bayley Scales of Infant and Toddler Development, Third Edition. We used linear regression and generalized additive models.
resultsOf 599 mothers, 175 (29%) met the inclusion criteria. Maternal urine cotinine levels were low (mean: 10.3 ng/mL, SD: 11.7 ng/mL). Reported passive smoking from different sources was strongly associated with urine cotinine levels. A negative association was observed between cotinine levels in pregnancy and child's gross motor function (beta = -3.22 per 10 ng/mL, 95% CI -5.09 to -1.34) after adjusting for factors potentially associated with neurodevelopment; results were similar in both sexes. A negative association was also observed for cognitive and receptive communication scales but the effect was small and not statistically significant.
conclusionsMaternal exposure during pregnancy to second-hand smoke measured through urine cotinine was associated with a decrease in gross motor function among 18-month-old children, even at low levels of exposure.
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