Evidence map›Paper›PMID 25863244›Full record

ArticleCell metabolism2015

One small step for muscle: a new micropeptide regulates performance.

Joanne Tonkin, Nadia Rosenthal

Abstract readComment
PubMed Publisher
In one paragraph

Article in Cell metabolism, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Joanne TonkinNational Heart and Lung Institute, Imperial Centre for Translational and Experimental Medicine, Imperial College London, London W12 0NN, UK.
Nadia RosenthalNational Heart and Lung Institute, Imperial Centre for Translational and Experimental Medicine, Imperial College London, London W12 0NN, UK; Australian Regenerative Medicine Institute/ EMBL Australia, Monash University, 3800 Melbourne, Australia. Electronic address: n.rosenthal@imperial.ac.uk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Micropeptides represent an emerging class of eukaryotic regulators that are easily missed in conventional genome annotation. Anderson et al. (2015) describe how a new tissue-specific micropeptide, myoregulin (MLN), interacts with the skeletal muscle calcium handling machinery to moderate contractile activity, representing a promising drug target for improving muscle performance.

Indexed as

AnimalsHumansMaleMuscle ProteinsMuscle, SkeletalRNA, Long NoncodingMuscle ProteinsRNA, Long Noncoding

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.