ArticleCell metabolism2015
Apple or pear: size and shape matter.
Article in Cell metabolism, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02728635 (Epigenetic Regulation of Human Adipose Tissue Distribution), which is not on this map. Cited by 21 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Epigenetic Regulation of Human Adipose Tissue Distribution
Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Metabolic aspects of surgical subcutaneous fat removal: An umbrella review and implications for future research.Biomolecules & biomedicine · 2023Pooled it
- The underexplored links between cancer and the internal body climate: Implications for cancer prevention and treatment.Frontiers in oncology · 2022Pooled it
- C/EBP α is Essential for Gonadal but Not Inguinal White Adipose Tissue Formation in Mice.Obesity (Silver Spring, Md.) · 2026Article
- Serpina3c Mitigates Adipose Tissue Inflammation by Inhibiting the HIF1α-Mediated Endoplasmic Reticulum Overoxidation in Adipocytes.Diabetes & metabolism journal · 2026Article
- Time-varying confounders in association between general and central obesity and coronary heart disease: Longitudinal targeted maximum likelihood estimation on atherosclerosis risk in communities study.Global epidemiology · 2025Article
- Article
- Adipose Tissue Hyperplasia and Hypertrophy in Common and Syndromic Obesity-The Case of BBS Obesity.Nutrients · 2023Review
- Population-based references for waist and hip circumferences, waist-to-hip and waist-to-height ratios for children and adolescents, and evaluation of their predictive ability.European journal of pediatrics · 2023Article
- Association of the android to gynoid fat ratio with nonalcoholic fatty liver disease: a cross-sectional study.Frontiers in nutrition · 2023Article
- High-Risk Obesity Phenotypes: Target for Multimorbidity Prevention at the ROFEMI Study.Journal of clinical medicine · 2022Article
- Causal associations between urinary sodium with body mass, shape and composition: a Mendelian randomization study.Scientific reports · 2020Article
- Omics Biomarkers in Obesity: Novel Etiological Insights and Targets for Precision Prevention.Current obesity reports · 2020Review
- Body shape, fear of falling, physical performance, and falls among individuals aged 55 years and above.European geriatric medicine · 2019Article
- Pancreatitis: TIGAR-O Version 2 Risk/Etiology Checklist With Topic Reviews, Updates, and Use Primers.Clinical and translational gastroenterology · 2019Review
- Article
- Body-weight dependent dose coefficients for adults exposed to idealised external photon fields.Journal of radiological protection : official journal of the Society for Radiological Protection · 2018Article
- Association of obesity, diabetes and hypertension with cognitive impairment in older age.Clinical epidemiology · 2018Article
- Deciphering adipose tissue heterogeneity.Annals of the New York Academy of Sciences · 2018Review
- Ovarian hormones and obesity.Human reproduction update · 2017Review
- Thermogenic profiling using magnetic resonance imaging of dermal and other adipose tissues.JCI insight · 2016Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Obesity-related morbidity and mortality are related to fat accumulation and fat distribution in humans. Two large-scale meta-analyses recently published in Nature by Shungin et al. (2015) and Locke et al. (2015) report novel genetic associations for central and overall obesity; these greatly advance our understanding of the biology of obesity.
Indexed as
Identifiers
25863240What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.