Evidence map›Paper›PMID 25862988›Full record

ArticleClinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association2016

Trends in Hospitalization for Diverticulitis and Diverticular Bleeding in the United States From 2000 to 2010.

Chelle L Wheat, Lisa L Strate

Open access · bronzeAbstract read
In one paragraph

Article in Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 87 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
87citing papers in PubMed, 4 pooled it
11.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

87 citing papers in PubMed, 4 syntheses or guidelines pooled it, 178 citations in OpenAlex.

  1. Pooled it
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  14. Observational
  15. Menopause and gastrointestinal health and disease.Nature reviews. Gastroenterology & hepatology · 2025
    Review
  16. The Epidemiology of Diverticulitis.Clinics in colon and rectal surgery · 2025
    Review
  17. Review
  18. Review
  19. Article
  20. Article

27 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Chelle L WheatDivision of Gastroenterology, Department of Medicine, University of Washington, Seattle, Washington; School of Public Health, Department of Health Services, University of Washington, Seattle, Washington.
Lisa L StrateDivision of Gastroenterology, Department of Medicine, University of Washington, Seattle, Washington; Harborview Medical Center, Seattle, Washington. Electronic address: lstrate@uw.edu.
University of Washington · US

Funding

Inflammation and Risk of DiverticulitisR01DK101495 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI CHAN, ANDREW T, STRATE, LISA L · 2014 to 2022
$4.4M
Intestinal Microbiota in Diverticular DiseaseR01DK084157 · NIDDK · UNIVERSITY OF WASHINGTON · PI STRATE, LISA L · 2010 to 2014
$1.7M
Genetic and Lifestyle Factors and Risk of Gastrointestinal BleedingR01DK095964 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI CHAN, ANDREW T · 2013 to 2015
$913k
NIDDK NIH HHS R01 DK084157NIDDK NIH HHS R01DK084157NIDDK NIH HHS R01 DK095964NIDDK NIH HHS R01 DK101495
6 · The paper itself

Abstract

BACKGROUND &

aimsMost studies of trends in diverticular disease have focused on diverticulitis or on a composite outcome of diverticulitis and bleeding. We aimed to quantify and compare the prevalence of hospitalization for diverticular bleeding and diverticulitis overall and by sex and race.

methodsWe analyzed data from the Nationwide Inpatient Sample from 2000 through 2010. We identified adult patients with a discharge diagnosis of diverticular bleeding or diverticulitis. By using yearly US intercensal data, we calculated age-, sex-, and race-specific rates, as well as age-adjusted prevalence rates.

resultsThe prevalence of hospitalizations per 100,000 persons for diverticular bleeding decreased over the 10-year period from 32.5 to 27.1 (-5.4; 95% confidence interval, -5.1 to -5.7). The prevalence of hospitalizations for diverticulitis peaked in 2008 (74.1/100,000 in 2000, 96.0/100,000 in 2008, and 91.9/100,000 in 2010). The prevalence of diverticulitis was higher in women than in men, whereas women and men had similar rates of diverticular bleeding. The prevalence of diverticular bleeding was highest in blacks (34.4/100,000 in 2010); whereas the prevalence of diverticulitis was highest in whites (75.5/100,000 in 2010).

conclusionsOver the past 10 years, the prevalence of hospitalizations for diverticulitis increased and then plateaued, whereas that of diverticular bleeding decreased. The prevalence according to sex and race differed for diverticulitis and diverticular bleeding. These findings indicate different mechanisms of pathogenesis for these disorders.

Indexed as

HospitalizationAdolescentAdultAgedAged, 80 and overDiverticulitisEthnicityFemaleGastrointestinal HemorrhageHumansMaleMiddle AgedPrevalenceSex FactorsUnited StatesYoung AdultComplicationsEpidemiologyPrevalenceRaceSex

Identifiers

PMID25862988
PMCPMC4624035
OpenAlexW2057031856

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.