Evidence map›Paper›PMID 25862077›Full record

ArticleMicrobes and infection2015

Beyond microbial community composition: functional activities of the oral microbiome in health and disease.

Ana E Duran-Pinedo, Jorge Frias-Lopez

Abstract read
In one paragraph

Article in Microbes and infection, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 99 papers.

0numbers the graph read from it
0cells of the map it votes in
99citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

99 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Exploring the Role of Oral Microbiota in the Pathophysiology and Treatment of Bruxism.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Review
  20. Review

39 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ana E Duran-PinedoDepartment of Microbiology, The Forsyth Institute, 245 First Street, Cambridge, MA 02142, USA.
Jorge Frias-LopezDepartment of Microbiology, The Forsyth Institute, 245 First Street, Cambridge, MA 02142, USA; Department of Oral Medicine, Infection, and Immunity, Harvard School of Dental Medicine, 188 Longwood Ave, Boston, MA 02115, USA. Electronic address: jfriaslopez@forsyth.org.

Funding

Biomarkers of Periodontal Disease ProgressionU01DE021127 · NIDCR · ADA FORSYTH INSTITUTE, INC. · PI TELES, RICARDO P · 2010 to 2016
$16.2M
Metatramscriptome of the Oral Microbiome During Periodontal Disease ProgressionR01DE021553 · NIDCR · UNIVERSITY OF FLORIDA · PI FRIAS-LOPEZ, JORGE · 2010 to 2020
$4.3M
NIDCR NIH HHS DE021127NIDCR NIH HHS DE021553NIDCR NIH HHS R01 DE021553NIDCR NIH HHS U01 DE021127
6 · The paper itself

Abstract

The oral microbiome plays a relevant role in the health status of the host and is a key element in a variety of oral and non-oral diseases. Despite advances in our knowledge of changes in microbial composition associated with different health conditions the functional aspects of the oral microbiome that lead to dysbiosis remain for the most part unknown. In this review, we discuss the progress made towards understanding the functional role of the oral microbiome in health and disease and how novel technologies are expanding our knowledge on this subject.

Indexed as

Health StatusOral HealthDental CariesGastrointestinal MicrobiomeHost-Pathogen InteractionsHumansMetagenomeCariesDysbiosisMicrobiomeOmicsOralPeriododontitis

Identifiers

PMID25862077
PMCPMC4495649

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.