ArticleBioinformatics (Oxford, England)2015
Cellular phenotype database: a repository for systems microscopy data.
Article in Bioinformatics (Oxford, England), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Ontology-based prediction of cancer driver genes.Scientific reports · 2019Article
- Systematic exploration of cell morphological phenotypes associated with a transcriptomic query.Nucleic acids research · 2018Article
- The anatomy of phenotype ontologies: principles, properties and applications.Briefings in bioinformatics · 2018Article
- How can functional annotations be derived from profiles of phenotypic annotations?BMC bioinformatics · 2017Article
- Metadata management for high content screening in OMERO.Methods (San Diego, Calif.) · 2016Article
- The cellular microscopy phenotype ontology.Journal of biomedical semantics · 2016Article
- Publishing and sharing multi-dimensional image data with OMERO.Mammalian genome : official journal of the International Mammalian Genome Society · 2015Article
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Authors and funding
4 authors.
Funding
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Abstract
motivationThe Cellular Phenotype Database (CPD) is a repository for data derived from high-throughput systems microscopy studies. The aims of this resource are: (i) to provide easy access to cellular phenotype and molecular localization data for the broader research community; (ii) to facilitate integration of independent phenotypic studies by means of data aggregation techniques, including use of an ontology and (iii) to facilitate development of analytical methods in this field.
resultsIn this article we present CPD, its data structure and user interface, propose a minimal set of information describing RNA interference experiments, and suggest a generic schema for management and aggregation of outputs from phenotypic or molecular localization experiments. The database has a flexible structure for management of data from heterogeneous sources of systems microscopy experimental outputs generated by a variety of protocols and technologies and can be queried by gene, reagent, gene attribute, study keywords, phenotype or ontology terms. AVAILABILITY AND IMPLEMENTATION: CPD is developed as part of the Systems Microscopy Network of Excellence and is accessible at http://www.ebi.ac.uk/fg/sym. CONTACT: jes@ebi.ac.uk or ugis@ebi.ac.uk SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.