Evidence map›Paper›PMID 25861945›Full record

ArticleDrug and alcohol dependence2015

Evidence of injection drug use in Kisumu, Kenya: Implications for HIV prevention.

Jennifer L Syvertsen, Kawango Agot, Spala Ohaga, Steffanie A Strathdee, Carol S Camlin, Eunice Omanga, Petronilla Odonde, Grace Rota, Kelvin Akoth, Juan Peng and 1 more

Open access · greenAbstract read
In one paragraph

Article in Drug and alcohol dependence, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 4 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 4 syntheses or guidelines pooled it, 31 citations in OpenAlex.

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  16. The Opioid Epidemic in Africa And Its Impact.Current addiction reports · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 2 countries.

Jennifer L SyvertsenDepartment of Anthropology, The Ohio State University, 4046 Smith Laboratory 174W. 18th Ave., Columbus, OH 43210-1106, USA. Electronic address: Syvertsen.1@osu.edu.
Kawango AgotImpact Research and Development Organization, P.O. Box 9171-40141, Kisumu, Kenya.
Spala OhagaImpact Research and Development Organization, P.O. Box 9171-40141, Kisumu, Kenya.
Steffanie A StrathdeeDivision of Global Public Health, University of California, San Diego, Central Research Services Facility (CRSF), La Jolla, CA 92093-0507, USA.
Carol S CamlinDepartment of Obstetrics, Gynecology & Reproductive Sciences and Center for AIDS Prevention Studies, University of California at San Francisco, 550 16th St., 3rd Floor [UCSF Mailcode 1224], San Francisco, CA 94158-2549 USA.
Eunice OmangaImpact Research and Development Organization, P.O. Box 9171-40141, Kisumu, Kenya.
Petronilla OdondeImpact Research and Development Organization, P.O. Box 9171-40141, Kisumu, Kenya.
Grace RotaKenya Medical Research Institute, P.O. Box 614-40100, Kisumu, Kenya.
Kelvin AkothKenya Medical Research Institute, P.O. Box 614-40100, Kisumu, Kenya.
Juan PengCenter for Biostatistics, The Ohio State University, 2012 Kenny Road, Columbus, OH 43221 USA.
Karla D WagnerSchool of Community Health Sciences, University of Nevada, Reno, 1664N. Virginia St. MS 0274, Reno, NV 89557, USA.
Impact Research and Development Organization · KEKenya Medical Research Institute · KEThe Ohio State University · USSan Francisco AIDS Foundation · USUniversity of California, San Diego · USUniversity of Nevada, Reno · US

Funding

Virology CoreP30AI027763 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI STEVEN Grant DEEKS · 1988 to 2026
$93.6M
The Ohio State University Center for clinical and Translational ScienceUL1TR001070 · NCATS · OHIO STATE UNIVERSITY · PI JACKSON, REBECCA D · 2013 to 2017
$22.6M
Training Program in Substance Use, HIV and Related InfectionsT32DA023356 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Natasha Martin, Steffanie A Strathdee · 2007 to 2026
$7.8M
University of California Global Health Institute Program for Fellows and ScholarsR25TW009343 · FIC · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI COHEN, CRAIG R, STRATHDEE, STEFFANIE A. · 2012 to 2017
$6.4M
Sex/Drug Tourism at the US/Mexico Border: Social Network Influences on HIV Risk.K01DA031031 · NIDA · UNIVERSITY OF NEVADA RENO · PI WAGNER, KARLA D. · 2010 to 2014
$882k
FIC NIH HHS R25 TW009343NCATS NIH HHS UL1 TR001070NCATS NIH HHS UL1TR001070NIAID NIH HHS P30 AI027763NIDA NIH HHS K01 DA031031NIDA NIH HHS T32 DA023356
6 · The paper itself

Abstract

backgroundInjection drug use is increasingly contributing to the HIV epidemic across sub-Saharan Africa. This paper provides the first descriptive analysis of injection drug use in western Kenya, where HIV prevalence is already highest in the nation at 15.1%.

methodsWe draw on quantitative data from a study of injection drug use in Kisumu, Kenya. We generated descriptive statistics on socio-demographics, sexual characteristics, and drug-related behaviors. Logistic regression models were adjusted for sex to identify correlates of self-reported HIV positive status.

resultsOf 151 participants, mean age was 28.8 years, 84% (n = 127) were male, and overall self-reported HIV prevalence reached 19.4%. Women had greater than four times the odds of being HIV positive relative to men (Odds Ratio [OR] 4.5, CI: 1.7, 11.8, p = .003). Controlling for sex, ever experiencing STI symptoms (Adjusted Odds ratio [AOR] 4.6, 95% CI 1.7, 12.0, p = .002) and sharing needles or syringes due to lack of access (AOR 3.6, 95% CI 1.2, 10.5, p = .02) were significantly associated with HIV positive status. Lower education (AOR 2.3, 95% CI 0.9, 5.6, p=.08), trading sex for drugs (AOR 2.8, 95% CI 0.9, 8.8, p = .08), being injected by a peddler (AOR 2.9, 95% CI 1.0, 8.5, p = .05), and injecting heroin (AOR 2.3, 95% CI 1.0, 5.7, p = .06), were marginally associated with HIV.

conclusionsThis exploratory study identified patterns of unsafe drug injection and concurrent sexual risk in western Kenya, yet few resources are currently available to address addiction or injection-related harm. Expanded research, surveillance, and gender sensitive programming are needed.

Indexed as

AdultFemaleHeroin DependenceHIV InfectionsHIV SeropositivityHumansKenyaMaleNeedle SharingPrevalenceRisk-TakingSex FactorsSexual BehaviorSocioeconomic FactorsSubstance Abuse, IntravenousSubstance-Related DisordersGenderHarm reductionHeroinHIV interventionsSexual risksub-Saharan Africa

Identifiers

PMID25861945
PMCPMC4447587
OpenAlexW2069264369

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.