Observational studyEuropean radiology2015
Diagnostic utility of Acoustic Radiation Force Impulse (ARFI) imaging in primary Sjoegren`s syndrome.
Observational study in European radiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Does ultrasound elastography have a role as a diagnostic method for Sjögren's syndrome in the salivary glands? A systematic review.Oral radiology · 2024Pooled it
- The diagnostic performance of salivary gland ultrasound elastography in Sjögren's syndrome and sicca symptoms: a systematic review and meta-analysis.European radiology · 2024Pooled it
- Multimodal Elastography of the Main Salivary Glands-A Narrative Review.Diagnostics (Basel, Switzerland) · 2025Review
- Proposal for standardized ultrasound analysis of the salivary glands: Part 1 submandibular gland.Laryngoscope investigative otolaryngology · 2024Article
- Combination of ultra-micro angiography and sound touch elastography for diagnosis of primary Sjögren's syndrome: a diagnostic test.Quantitative imaging in medicine and surgery · 2023Article
- Point Shear Wave Elastography in Diagnosis and Follow-Up of Salivary Gland Affection after Head and Neck Cancer Treatment.Journal of clinical medicine · 2022Article
- Shear wave elastography as a potential additional diagnostic tool in primary Sjögren's syndrome: an observational study.Rheumatology international · 2022Observational
- Multimodal Evaluation of Long-Term Salivary Gland Alterations in Sarcoidosis.Journal of clinical medicine · 2022Article
- Inhalative Treatment of Laryngitis Sicca in Patients with Sjögren's Syndrome-A Pilot Study.Journal of clinical medicine · 2022Article
- Salivary Gland Ultrasound in Primary Sjögren's Syndrome: Current and Future Perspectives.Open access rheumatology : research and reviews · 2022Review
- Effectiveness of ultrasonography and shear wave sonoelastography in Sjögren syndrome with salivary gland involvement.Ultrasonography (Seoul, Korea) · 2021Article
- Narrative review of multiparametric ultrasound in parotid gland evaluation.Gland surgery · 2020Review
- Strain and shear wave ultrasound elastography in evaluation of chronic inflammatory disorders of major salivary glands.Dento maxillo facial radiology · 2020Article
- The Utility of Major Salivary Gland Ultrasonographic Parameters in the Diagnosis of Sjögren Syndrome.Disease markers · 2019Article
- Combined classification system based on ACR/EULAR and ultrasonographic scores for improving the diagnosis of Sjögren's syndrome.PloS one · 2018Article
- Article
- Effect of liposomal local therapy on salivary glands in acoustic radiation force impulse imaging in Sjögren's syndrome.Clinical rheumatology · 2016Article
- Article
- Combination of Salivary Gland Ultrasonography and Virtual Touch Quantification for Diagnosis of Sjögren's Syndrome: A Preliminary Study.BioMed research international · 2016Article
- Making the diagnosis of Sjögren's syndrome in patients with dry eye.Clinical ophthalmology (Auckland, N.Z.) · 2016Review
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe purpose of the study was to assess the diagnostic utility of acoustic radiation force impulse (ARFI) imaging in primary Sjögren's syndrome (pSS).
methodsOne hundred fifty-seven patients with sicca symptoms and/or salivary gland swelling were included. Sicca symptoms, Schirmer test, unstimulated whole saliva (UWS), SS-A/B antibodies, and histology were assessed according to American-European Consensus group (AECG) criteria. All patients underwent high-resolution ultrasound and ARFI imaging of the parotid (PG) and submandibular glands (SMG).
resultsSeventy patients were classified as having pSS. The remaining 87 patients suffered from idiopathic sicca (n = 24), rheumatoid arthritis (n = 12), sarcoidosis (n = 9), cutaneous/systemic lupus erythematosus (n = 7), scleroderma (n = 2), dermatomyositis (n = 1), HBV/HCV (n = 2), and panarteritis nodosa (n = 1), and disorders in 29 patients were classified as not otherwise specified. ARFI values of the PG were significantly higher in the pSS versus non-pSS groups (2.86 ± 0.07 m/s vs. 2.15 ± 0.11 m/s, p < 0.0001). ARFI imaging demonstrated diagnostic sensitivity and specificity of 81 % and 67 %, respectively.
conclusionsIn addition to histology, ARFI imaging was the most important diagnostic tool for identifying early pSS. KEY POINTS: • Early stages in Sjögren's syndrome become apparent with major salivary gland enlargements. • Schirmer and unstimulated whole saliva tests demonstrated insufficient sensitivity/specificity for early-stage diagnosis. • Acoustic radiation force impulse imaging is a reliable tool for diagnosing early disease stages.
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