ArticleAnnals of medical and health sciences research
Cytokeratin 19 expression patterns of dentigerous cysts and odontogenic keratocysts.
Article in Annals of medical and health sciences research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 13 citations in OpenAlex.
- SOX2 and cytokeratins 5, 8 and 18 as potential stem cell biomarkers in botryoid odontogenic, lateral periodontal and gingival cysts.Histology and histopathology · 2026Article
- Immunohistochemical Characterization of Reactive Epithelial Changes in Odontogenic Keratocysts.Pathology oncology research : POR · 2020Article
- A Comparative Analysis of Cytokeratin 18 and 19 Expressions in Odontogenic Keratocyst, Dentigerous Cyst and Radicular Cyst with a Review of Literature.Journal of clinical and diagnostic research : JCDR · 2016Article
- The importance of ctokeratins in the early detection of oral squamous cell carcinoma.Journal of oral and maxillofacial pathology : JOMFPArticle
- Cytokeratin and fibronectin expression in orthokeratinized odontogenic cyst: A comparative immunohistochemical study.Journal of oral and maxillofacial pathology : JOMFPArticle
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2 authors at 1 institution in 1 country.
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Abstract
backgroundAlthough numerous investigators have studied the pattern of keratin expression in different odontogenic cysts, the results have been variable.
aimThe present study was conducted to determine the pattern of expression of cytokeratin 19 (CK 19) in the epithelial lining of odontogenic keratocysts and dentigerous cysts. MATERIALS AND
methodsThe epithelial layers showing expression of the epithelial marker CK 19 was determined by immunohistochemical methods in 15 tissue specimens each of histopathologically confirmed cases of dentigerous cysts and odontogenic keratocysts. Statistical analysis was done to compare the CK 19 expression between dentigerous cyst and odontogenic keratocyst using the Chi-square test. P < 0.05 was considered to be statistically significant.
resultsAll specimens of dentigerous cysts were positive for CK 19 with 20% (3/15) of the specimens showing expression only in a single layer of the epithelium, 40% (6/15) of the specimens showing expression in more than one layer but not the entire thickness of the epithelium, and the remaining 40% (6/15) showing expression throughout the entire thickness of the epithelium. In the case of odontogenic keratocysts, 40% (6/15) of the specimens were negative for CK 19, 40% (6/15) of the specimens showed expression only in a single layer of the epithelium, and 20% (3/15) of the specimens showed expression in more than one layer, but not the entire thickness of the epithelium. The observed differences in CK 19 expression by the two lesions were statistically significant (P < 0.01).
conclusionThe differences in CK 19 expression by these cysts may be utilized as a diagnostic tool in differentiating between these two lesions.
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