ArticleInsects2013
Immune Signaling and Antimicrobial Peptide Expression in Lepidoptera.
Article in Insects, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 49 citations in OpenAlex.
- Beyond silkworms: translating molecular mechanisms of pesticide toxicity from Bombyx mori to lepidopteran pest management.Pest management science · 2026Review
- The essential role of gut microbiota in dsRNA-mediated pest control of the phytophagous ladybird beetle, Henosepilachna vigintioctopunctata.NPJ biofilms and microbiomes · 2025Article
- Regulatory networks of mRNAs and miRNAs involved in the immune response of diamondback moth, Plutella xylostella to fungal infection.BMC genomics · 2025Article
- The humoral immune response of the lepidopteran model insect, silkwormCurrent research in insect science · 2024Review
- Parasitic nematode secreted phospholipase AFrontiers in immunology · 2023Article
- Induction of Multiple Immune Signaling Pathways inViruses · 2022Article
- Compatibility of mycorrhiza-induced resistance with viral and bacterial entomopathogens in the control of Spodoptera exigua in tomato.Pest management science · 2022Article
- Article
- Comparative transcriptomics of albino and warningly-coloured caterpillars.Ecology and evolution · 2021Article
- In vivo transcriptome analysis provides insights into host-dependent expression of virulence factors by Yersinia entomophaga MH96, during infection of Galleria mellonella.G3 (Bethesda, Md.) · 2021Article
- Bioprospecting for Antibacterial Drugs: a Multidisciplinary Perspective on Natural Product Source Material, Bioassay Selection and Avoidable Pitfalls.Pharmaceutical research · 2020Review
- Article
- Exploring the Role of Relish on Antimicrobial Peptide Expressions (AMPs) Upon Nematode-Bacteria Complex Challenge in the Nipa Palm Hispid Beetle,Frontiers in microbiology · 2019Article
- Ready or Not: Microbial Adaptive Responses in Dynamic Symbiosis Environments.Journal of bacteriology · 2017Review
- High Levels of the Xenorhabdus nematophila Transcription Factor Lrp Promote Mutualism with the Steinernema carpocapsae Nematode Host.Applied and environmental microbiology · 2017Article
- RNAseq Analysis of theG3 (Bethesda, Md.) · 2017Article
- Parasitic Nematode Immunomodulatory Strategies: Recent Advances and Perspectives.Pathogens (Basel, Switzerland) · 2016Review
- Characterization and regulation of expression of an antifungal peptide from hemolymph of an insect, Manduca sexta.Developmental and comparative immunology · 2016Article
- Genome-wide characterization and expression profiling of immune genes in the diamondback moth, Plutella xylostella (L.).Scientific reports · 2015Article
- Microbial population dynamics in the hemolymph of Manduca sexta infected with Xenorhabdus nematophila and the entomopathogenic nematode Steinernema carpocapsae.Applied and environmental microbiology · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Many lepidopteran insects are agricultural pests that affect stored grains, food and fiber crops. These insects have negative ecological and economic impacts since they lower crop yield, and pesticides are expensive and can have off-target effects on beneficial arthropods. A better understanding of lepidopteran immunity will aid in identifying new targets for the development of specific insect pest management compounds. A fundamental aspect of immunity, and therefore a logical target for control, is the induction of antimicrobial peptide (AMP) expression. These peptides insert into and disrupt microbial membranes, thereby promoting pathogen clearance and insect survival. Pathways leading to AMP expression have been extensively studied in the dipteran Drosophila melanogaster. However, Diptera are an important group of pollinators and pest management strategies that target their immune systems is not recommended. Recent advances have facilitated investigation of lepidopteran immunity, revealing both conserved and derived characteristics. Although the general pathways leading to AMP expression are conserved, specific components of these pathways, such as recognition proteins have diverged. In this review we highlight how such comparative immunology could aid in developing pest management strategies that are specific to agricultural insect pests.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.