Evidence map›Paper›PMID 25861452›Full record

ArticleJournal of pharmaceutical policy and practice2015

Knowledge and perceptions of physicians from private medical centres towards generic medicines: a nationwide survey from Malaysia.

Rohit Kumar, Mohamed Azmi Hassali, Fahad Saleem, Alian A Alrasheedy, Navneet Kaur, Zhi Yen Wong, Muhamad Ali Sk Abdul Kader

Abstract read
In one paragraph

Article in Journal of pharmaceutical policy and practice, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  12. The Impact of Information on Doctors' Attitudes Toward Generic Drugs.Inquiry : a journal of medical care organization, provision and financing · 2016
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Rohit KumarDiscipline of Administrative and Social Pharmacy, School of Pharmaceutical Sciences, Universiti Sains Malaysia, Penang, 11800 Malaysia.
Mohamed Azmi HassaliDiscipline of Administrative and Social Pharmacy, School of Pharmaceutical Sciences, Universiti Sains Malaysia, Penang, 11800 Malaysia.
Fahad SaleemDiscipline of Administrative and Social Pharmacy, School of Pharmaceutical Sciences, Universiti Sains Malaysia, Penang, 11800 Malaysia.
Alian A AlrasheedyPharmacy Practice Department, College of Pharmacy, Qassim University, Qassim, Saudi Arabia.
Navneet KaurDiscipline of Physiology and Pharmacology, School of Pharmaceutical Sciences, Universiti Sains Malaysia, Penang, 11800 Malaysia.
Zhi Yen WongPharmacy Department, Hospital Teluk, Intan, Perak Malaysia.
Muhamad Ali Sk Abdul KaderDepartment of Cardiology, Hospital Pulau Pinang, Jalan Residensi, 10990 Penang Malaysia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesGeneric medicine prescribing has become a common practice in public hospitals. However, the trend in private medical centres seems to be different. The objective of this study was to investigate knowledge, perceptions and behavior of physicians from private medical centres in Malaysia regarding generic medicines.

methodsThis study was a cross-sectional nationwide survey targeting physicians from private medical centres in Malaysia. The survey was conducted using questionnaire having (i) background and demographic data of the physicians, volume of prescription in a day, stock of generic medicines in their hospital pharmacy etc. (ii) their knowledge about bioequivalence (iii) prescribing behavior (iv) physicians' knowledge of quality, safety and efficacy of generic medicines, and their cost (v) perceptions of physicians towards issues pertaining to generic medicines utilization.

resultsA total of 263 questionnaires out of 735 were received, giving a response rate of 35.8%. Of the respondents, 214 (81.4%) were male and 49 (18.6%) were females. The majority of the participants were in the age range of 41-50 years and comprised 49.0% of the respondents. Only 2.3% of physicians were aware of the regulatory limits of bioequivalence standards in Malaysia. Of the respondents, 23.2% agreed that they 'always' write their prescriptions using originator product name whereas 50.2% do it 'usually'. A number of significant associations were found between their knowledge, perceptions about generic medicines and their demographic characteristics.

conclusionsThe majority of the physicians from private medical centres in Malaysia had negative perceptions about safety, quality and the efficacy of generic medicines. These negative perceptions could be the cause of the limited use of generic medicines in the private medical centres. Therefore, in order to facilitate their use, it is recommended that the physicians need to be reassured and educated about the drug regulatory authority approval system of generic medicines with regard to their bioequivalence, quality, efficacy and safety. Apart from the policy on generic substitution, it would also be recommended to have a national medicine pricing policy, which controls drug prices, in both the public and private sector. These efforts are worthwhile to reduce the drug expenditure and improve the medicine affordability in Malaysia.

Indexed as

GenericsMalaysiaPerceptionsPrivate hospitalsQuantitative

Identifiers

PMID25861452
PMCPMC4376509

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.