ArticleEvolutionary applications2015
Public health evolutionary biology of antimicrobial resistance: priorities for intervention.
Article in Evolutionary applications, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed.
- Phylogenetic Context of Antibiotic Resistance Provides Insights into the Dynamics of Resistance Emergence and Spread.The Journal of infectious diseases · 2025Article
- Tracing the evolutionary dynamics of carbapenem-resistant Escherichia coli in recurrent and multi-site infections.Gut pathogens · 2025Article
- Antimicrobial Resistance in the Global Health Network: Known Unknowns and Challenges for Efficient Responses in the 21st Century.Microorganisms · 2023Review
- Antimicrobial resistance: new insights and therapeutic implications.Applied microbiology and biotechnology · 2022Review
- Drug Repurposing of the Unithiol: Inhibition of Metallo-β-Lactamases for the Treatment of Carbapenem-Resistant Gram-Negative Bacterial Infections.International journal of molecular sciences · 2022Article
- Evolutionary Pathways and Trajectories in Antibiotic Resistance.Clinical microbiology reviews · 2021Article
- New Insight on Antibiotic Resistance and Virulence ofAntibiotics (Basel, Switzerland) · 2021Article
- Genomics ofFrontiers in microbiology · 2020Article
- Antibiotic Resistance: Moving From Individual Health Norms to Social Norms in One Health and Global Health.Frontiers in microbiology · 2020Review
- Five rules for resistance management in the antibiotic apocalypse, a road map for integrated microbial management.Evolutionary applications · 2019Review
- Simulating Multilevel Dynamics of Antimicrobial Resistance in a Membrane Computing Model.mBio · 2019Article
- Insights Into Non-coding RNAs as Novel Antimicrobial Drugs.Frontiers in genetics · 2019Review
- Mutual influence of secondary and key drug-resistance mutations on catalytic properties and thermal stability of TEM-type β-lactamases.FEBS open bio · 2018Article
- Environmental factors influencing the development and spread of antibiotic resistance.FEMS microbiology reviews · 2018Review
- Evolutionary biology and the risk of scrapie disease in sheep.Open veterinary journal · 2018Review
- Antibiotic resistance: it's bad, but why isn't it worse?BMC biology · 2017Review
- Genomic sequencing of Neisseria gonorrhoeae to respond to the urgent threat of antimicrobial-resistant gonorrhea.Pathogens and disease · 2017Review
- Lateral Antimicrobial Resistance Genetic Transfer is active in the open environment.Scientific reports · 2017Article
- Antimicrobial resistance and universal health coverage.BMJ global health · 2017Review
- Editorial: The Global Challenge Posed by the Multiresistant International Clones of Bacterial Pathogens.Frontiers in microbiology · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
The three main processes shaping the evolutionary ecology of antibiotic resistance (AbR) involve the emergence, invasion and occupation by antibiotic-resistant genes of significant environments for human health. The process of emergence in complex bacterial populations is a high-frequency, continuous swarming of ephemeral combinatory genetic and epigenetic explorations inside cells and among cells, populations and communities, expanding in different environments (migration), creating the stochastic variation required for evolutionary progress. Invasion refers to the process by which AbR significantly increases in frequency in a given (invaded) environment, led by external invaders local multiplication and spread, or by endogenous conversion. Conversion occurs because of the spread of AbR genes from an exogenous resistant clone into an established (endogenous) bacterial clone(s) colonizing the environment; and/or because of dissemination of particular resistant genetic variants that emerged within an endogenous clonal population. Occupation of a given environment by a resistant variant means a permanent establishment of this organism in this environment, even in the absence of antibiotic selection. Specific interventions on emergence influence invasion, those acting on invasion also influence occupation and interventions on occupation determine emergence. Such interventions should be simultaneously applied, as they are not simple solutions to the complex problem of AbR.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.