ArticleEvidence-based complementary and alternative medicine : eCAM2015
Antiviral Action of Hydromethanolic Extract of Geopropolis from Scaptotrigona postica against Antiherpes Simplex Virus (HSV-1).
Article in Evidence-based complementary and alternative medicine : eCAM, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 61 citations in OpenAlex.
- Antiviral activity of the aqueous extract of twelve monthly-collections of propolis from Barra do Corda.Scientific reports · 2026Article
- Geopropolis fromPharmaceuticals (Basel, Switzerland) · 2026Article
- Quality assessment and chemical diversity of Australian propolis from Tetragonula carbonaria and Tetragonula hockingsi stingless bees.Scientific reports · 2025Article
- Antiviral action of aqueous extracts of propolis from Scaptotrigona aff. postica (Hymenoptera; Apidae) against Zica, Chikungunya, and Mayaro virus.Scientific reports · 2024Article
- Analysis of Pyrrolizidine Alkaloids in Stingless Bee Honey and Identification of a Botanical Source asToxins · 2024Article
- Differences in the biochemical content and radical scavenging activity of propolis from different parts of aRoyal Society open science · 2023Article
- Antiviral Activity of Flavonoids from Geopropolis of the Brazilian Jandaira Bee against Zika and Dengue Viruses.Pharmaceutics · 2023Article
- The Role of Propolis as a Natural Product with Potential Gastric Cancer Treatment Properties: A Systematic Review.Foods (Basel, Switzerland) · 2023Review
- Comparing the Effects of Encapsulated and Non-Encapsulated Propolis Extracts on Model Lipid Membranes and Lactic Bacteria, with Emphasis on the Synergistic Effects of Its Various Compounds.Molecules (Basel, Switzerland) · 2023Article
- Chemical Composition and Biological Activity of Argentinian Propolis of Four Species of Stingless Bees.Molecules (Basel, Switzerland) · 2022Article
- General Nutritional Profile of Bee Products and Their Potential Antiviral Properties against Mammalian Viruses.Nutrients · 2022Review
- Chemical Variability and Pharmacological Potential of Propolis as a Source for the Development of New Pharmaceutical Products.Molecules (Basel, Switzerland) · 2022Review
- Antiviral, Antibacterial, Antifungal, and Antiparasitic Properties of Propolis: A Review.Foods (Basel, Switzerland) · 2021Review
- How diverse is the chemistry and plant origin of Brazilian propolis?Apidologie · 2021Review
- Antiviral and virucidal activities ofHeliyon · 2019Article
- Evaluating Weathering of Food Packaging Polyethylene-Nano-clay Composites: Release of Nanoparticles and their Impacts.NanoImpact · 2018Article
- Insects: an underrepresented resource for the discovery of biologically active natural products.Acta pharmaceutica Sinica. B · 2017Review
- Chemical Profile and Antioxidant, Anti-Inflammatory, Antimutagenic and Antimicrobial Activities of Geopropolis from the Stingless Bee Melipona orbignyi.International journal of molecular sciences · 2017Article
- Antioxidant Activity of a Geopropolis from Northeast Brazil: Chemical Characterization and Likely Botanical Origin.Evidence-based complementary and alternative medicine : eCAM · 2017Article
- The ameliorative potential of ethanolic extract of propolis on hematotoxicity and structural neuronal damage in hyperthermia-exposed rats.Iranian journal of basic medical sciences · 2016Article
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The studies on chemical composition and biological activity of propolis had focused mainly on species Apis mellifera L. (Hymenoptera: Apidae). There are few studies about the uncommon propolis collected by stingless bees of the Meliponini tribe known as geopropolis. The geopropolis from Scaptotrigona postica was collected in the region of Barra do Corda, Maranhão state, Brazil. The chemical analysis of hydromethanolic extract of this geopropolis (HMG) was carried out through HPLC-DAD-ESI-MS/MS and the main constituents found were pyrrolizidine alkaloids and C-glycosyl flavones. The presence of alkaloids in extracts of propolis is detected for the first time in this sample. The antiviral activity of HMG was evaluated through viral DNA quantification experiments and electron microscopy experiments. Quantification of viral DNA from herpes virus showed reduction of about 98% in all conditions and concentration tested of the HMG extract. The results obtained were corroborated by transmission electron microscopy, in which the images did not show particle or viral replication complex. The antiviral activity of C-glycosyl flavones was reported for a variety of viruses, being observed at different points in the viral replication. This work is the first report about the antiviral activity of geopropolis from Scaptotrigona postica, in vitro, against antiherpes simplex virus (HSV).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.