Evidence map›Paper›PMID 25861356›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2015

Monitoring the Effects of Acupoint Antioxidant Intervention by Measuring Electrical Potential Difference along the Meridian.

Ming-Ming Xu, Jing-Ke Guo, Jin-Sen Xu, Chao-Xin Zhang, Shu-Tao Liu, Ri-Tao Liao, Chun-Tong Lin, Jian-Hui Guo, Ping-Fan Rao

Abstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Topical Application of TAT-Superoxide Dismutase in Acupoints LI 20 on Allergic Rhinitis.Evidence-based complementary and alternative medicine : eCAM · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ming-Ming XuCAS.SIBS-Zhejiang Gongshang University Joint Centre for Food and Nutrition Research, Zhejiang Gongshang University, Hangzhou 310018, China.
Jing-Ke GuoCAS.SIBS-Zhejiang Gongshang University Joint Centre for Food and Nutrition Research, Zhejiang Gongshang University, Hangzhou 310018, China.
Jin-Sen XuResearch Department of Meridian of Fujian Academy of TCM, Fuzhou 350003, China.
Chao-Xin ZhangCollege of Biological Science and Technology, Fuzhou University, Fuzhou 350108, China.
Shu-Tao LiuCollege of Biological Science and Technology, Fuzhou University, Fuzhou 350108, China.
Ri-Tao LiaoCollege of Biological Science and Technology, Fuzhou University, Fuzhou 350108, China.
Chun-Tong LinCollege of Biological Science and Technology, Fuzhou University, Fuzhou 350108, China.
Jian-Hui GuoCollege of Biological Science and Technology, Fuzhou University, Fuzhou 350108, China.
Ping-Fan RaoCAS.SIBS-Zhejiang Gongshang University Joint Centre for Food and Nutrition Research, Zhejiang Gongshang University, Hangzhou 310018, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous studies suggest that superoxide anions are possibly traveling along acupuncture meridians. The electrical potential difference (EPD) between acupoints may be related to the movement. To test the above hypothesis, we conducted a study investigating the effects of acupoint antioxidant interventions on the meridian EPD. Firstly, ST39 (L) and ST44 (L) were screened out for the EPD detection along the stomach meridian, and ST36 (L) was selected for interventions including acumassage with the control cream, as well as the TAT-SOD cream for 30 minutes, or injection with reduced glutathione sodium. The EPD between ST39 and ST44 was recorded for 80 minutes and measured again 48 h later. While the EPD increased during the acumassage, the acumassage with TAT-SOD cream and the glutathione injection generated waves of EPD increased, indicating the migration or removal from the visceral organ of a greater quantity of superoxide. Remarkably lower EPD readings 48 h later with both antioxidant acupoint interventions than the mere acumassage imply a more complete superoxide flushing out due to the restored superoxide pathway at the acupoint after interventions. The results confirm superoxide transportation along the meridians and demonstrate a possibility of acupoint EPD measurement as a tool to monitor changes in the meridians and acupoints.

Identifiers

PMID25861356
PMCPMC4377379

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.