ReviewInternational journal of endocrinology2015
The impact of sleep and circadian disturbance on hormones and metabolism.
Review in International journal of endocrinology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 169 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
169 citing papers in PubMed, 4 syntheses or guidelines pooled it, 334 citations in OpenAlex.
- Global research on 24-hour movement behaviours guidelines in children and adolescents: a systematic review.The international journal of behavioral nutrition and physical activity · 2025Pooled it
- The association between atopic dermatitis and linear growth in children- a systematic review.European journal of pediatrics · 2024Pooled it
- Pooled it
- Sleep and obesity among children: A systematic review of multiple sleep dimensions.Pediatric obesity · 2020Pooled it
- Trial
- Early Time-Restricted Eating Improves Weight Loss While Preserving Muscle: An 8-Week Trial in Young Women.Nutrients · 2025Trial
- Predictors of dream enactment behavior among medical students: The case of the University of Gondar, Ethiopia.PloS one · 2022Trial
- A pilot study to determine the short-term effects of milk with differing glycaemic properties on sleep among toddlers: a randomised controlled trial.BMC pediatrics · 2015Trial
- Self-Reported Chronotype and Diet Quality in Chinese Adolescents: Insights from a Cross-Sectional Study in Xiamen.Nutrients · 2026Article
- Sleep Architecture and Risk-Taking in Adolescents and Young Adults: Independent Contributions of REM Sleep, Sigma Activity, and Morning Cortisol.Behavioral sciences (Basel, Switzerland) · 2026Article
- Insomnia-Associated Circadian and Thrombotic Alterations Coincide with Morning Cardiac Vulnerability.ACS pharmacology & translational science · 2026Article
- Article
- Article
- Εndogenous metabolomic responses in circadian disrupted night shift working populations: a scoping review.Journal of the National Cancer Center · 2026Review
- Review
- Variation in sleep duration across latitudes and countries: a Bayesian hierarchical analysis of wearable data.Npj biological timing and sleep · 2026Article
- Article
- Paternal sleep deprivation and cardiac dysfunction in offspring: A perspective of myocardial hypertrophy.Experimental physiology · 2026Article
- Effectiveness of Melatonin-Containing Foods on Promoting Sleep: A Scoping Review.Food science & nutrition · 2026Review
- The Insulin-Urothelial Axis: Evaluating Insulin Resistance as a Convergent Driver of Bladder Cancer Across Diverse Risk Factor Profiles.International journal of molecular sciences · 2026Review
109 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The levels of several hormones fluctuate according to the light and dark cycle and are also affected by sleep, feeding, and general behavior. The regulation and metabolism of several hormones are influenced by interactions between the effects of sleep and the intrinsic circadian system; growth hormone, melatonin, cortisol, leptin, and ghrelin levels are highly correlated with sleep and circadian rhythmicity. There are also endogenous circadian mechanisms that serve to regulate glucose metabolism and similar rhythms pertaining to lipid metabolism, regulated through the actions of various clock genes. Sleep disturbance, which negatively impacts hormonal rhythms and metabolism, is also associated with obesity, insulin insensitivity, diabetes, hormonal imbalance, and appetite dysregulation. Circadian disruption, typically induced by shift work, may negatively impact health due to impaired glucose and lipid homeostasis, reversed melatonin and cortisol rhythms, and loss of clock gene rhythmicity.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.