Evidence map›Paper›PMID 25861258›Full record

ArticleGastroenterology research and practice2015

Association between Helicobacter pylori Infection and Chronic Urticaria: A Meta-Analysis.

Huiyuan Gu, Lin Li, Min Gu, Guoxin Zhang

Open access · goldAbstract read
In one paragraph

Article in Gastroenterology research and practice, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.

  1. Association betweenBMJ open · 2020
    Pooled it
  2. Selected Markers of Inflammation in the Saliva of Children Infected withInternational journal of molecular sciences · 2024
    Article
  3. Review
  4. Children (Basel, Switzerland) · 2022
    Review
  5. Frontiers in immunology · 2022
    Review
  6. Article
  7. Association BetweenClinical, cosmetic and investigational dermatology · 2021
    Article
  8. World journal of gastroenterology · 2020
    Review
  9. Article
  10. Association between Chronic Urticaria andDermatology research and practice · 2020
    Article
  11. Eradication ofPostepy dermatologii i alergologii · 2018
    Article
  12. Article
  13. Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Huiyuan GuDepartment of Gastroenterology, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.
Lin LiDepartment of Gastroenterology, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.
Min GuDepartment of Pediatrics, Changzhou Children's Hospital, Changzhou, Jiangsu 213003, China.ORCID 0000-0001-5450-558X
Guoxin ZhangDepartment of Gastroenterology, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.
Jiangsu Province Hospital · CNHangzhou Children's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background. Some studies have shown the possible involvement of Helicobacter pylori (H. pylori) infection in chronic urticaria, but the relationship remains controversial. The aim of this meta-analysis was to quantitatively assess the association between H. pylori infection and chronic urticaria. Methods. Observational studies comparing the prevalence of H. pylori infection in patients with chronic urticaria and control subjects were identified through a systematic search in MEDLINE and EMBASE up to July 2014. H. pylori infection was confirmed by serological or nonserological tests. For subgroup analyses, studies were separated by region, publication year, and H. pylori detection method to screen the potential factors resulting in heterogeneity. Results. 16 studies involving 965 CU cases and 1235 controls were included. Overall, the prevalence of H. pylori infection was higher in urticarial patients than in controls (OR = 1.66; 95% CI: 1.12-2.45; P = 0.01). This result persisted in subanalysis of nine high-quality studies (OR = 1.36; 95% CI: 1.03-1.80; P = 0.03). Subgroup analysis showed that detection method of H. pylori is also a potential influential factor for the overall results. Conclusions. Our present meta-analysis suggests that H. pylori infection is significantly, though weakly, associated with an increased risk of chronic urticaria.

Identifiers

PMID25861258
PMCPMC4378606
OpenAlexW2066390662

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.