Evidence map›Paper›PMID 25860429›Full record

ArticleNeurosurgery2015

Quantitative Magnetic Resonance Venography is Correlated With Intravenous Pressures Before and After Venous Sinus Stenting: Implications for Treatment and Monitoring.

Darian R Esfahani, Matthew Stevenson, Heather E Moss, Sepideh Amin-Hanjani, Victor Aletich, Sachin Jain, Fady T Charbel, Ali Alaraj

Abstract read
In one paragraph

Article in Neurosurgery, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Current Status of the Application of Intracranial Venous Sinus Stenting.International journal of medical sciences · 2015
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Darian R Esfahani*Department of Neurosurgery, University of Illinois at Chicago, Chicago, Illinois; ‡Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, Illinois; §Department of Neurology and Rehabilitation, University of Illinois at Chicago, Chicago, Illinois.
Matthew Stevenson
Heather E Moss
Sepideh Amin-Hanjani
Victor Aletich
Sachin Jain
Fady T Charbel
Ali Alaraj
University of Illinois Chicago · US

Funding

Translational Core for Therapeutic and Diagnostic DevelopmentP30EY001792 · NEI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI YAO, XINCHENG · 1985 to 2025
$14.8M
Physiologically Based Markers of Idiopathic Intracranial HypertensionK23EY024345 · NEI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI MOSS, HEATHER ELSPETH · 2014 to 2018
$1.1M
NEI NIH HHS K23 EY024345NEI NIH HHS P30 EY001792NEI NIH HHS P30 EY01792
6 · The paper itself

Abstract

backgroundEndovascular stenting is an effective treatment for patients with clinically significant cerebral venous sinus stenosis. Traditionally, stenting is indicated in elevated intravenous pressures on conventional venography; however, noninvasive monitoring is more desirable. Quantitative magnetic resonance angiography is an imaging modality that measures blood flow noninvasively. Established in the arterial system, applications to the venous sinuses have been limited.

objectiveTo examine quantitative magnetic resonance venography (qMRV) in the measurement of venous sinus flow in patients undergoing endovascular stenting and to identify a relationship with intravenous pressures.

methodsFive patients with intracranial hypertension secondary to venous sinus stenosis underwent cerebral venous stenting between 2009 and 2013 at a single institution. Preoperatively, venous sinus flow was determined by using qMRV, and intravenous pressure was measured during venography. After stenting, intravenous pressure, qMRV flow, and clinical outcomes were assessed and compared.

resultsA mean prestenotic intravenous pressure of 45.2 mm Hg was recorded before stenting, which decreased to 27.4 mm Hg afterward (Wilcoxon signed rank test P = .04). Total jugular outflow on qMRV increased by 260.2 mL/min. Analysis of the change in intravenous pressure and qMRV flow identified a linear relationship (Pearson correlation r = 0.926). All patients displayed visual improvement at 6 weeks.

conclusionVenous outflow by qMRV increases after endovascular stenting and correlates with significantly improved intravenous pressures. These findings introduce qMRV as a potential adjunct to measure venous flow after stenting, and as a plausible tool in the selection and postoperative surveillance of the patient who has cerebral venous sinus stenosis.

Indexed as

StentsAgedBlood PressureCerebrovascular CirculationConstriction, PathologicCranial SinusesEndovascular ProceduresFemaleHumansIntracranial HypertensionJugular VeinsMagnetic Resonance AngiographyMaleMiddle AgedPhlebographyTreatment Outcome

Identifiers

PMID25860429
PMCPMC4506216
OpenAlexW1969452037

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.