SynthesisEmerging infectious diseases2015
Global burden of invasive nontyphoidal Salmonella disease, 2010(1).
Synthesis in Emerging infectious diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 304 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
304 citing papers in PubMed, 5 syntheses or guidelines pooled it, 468 citations in OpenAlex.
- Invasive non-typhoidal Salmonella infections in China (1961-2024): a retrospective systematic analysis of multicentre case reports.Journal of global health · 2026Pooled it
- Pooled it
- Complications and mortality of non-typhoidal salmonella invasive disease: a global systematic review and meta-analysis.The Lancet. Infectious diseases · 2022Pooled it
- Incidence of non-typhoidal Salmonella invasive disease: A systematic review and meta-analysis.The Journal of infection · 2021Pooled it
- The global burden of non-typhoidal salmonella invasive disease: a systematic analysis for the Global Burden of Disease Study 2017.The Lancet. Infectious diseases · 2019Pooled it
- Safety and Immunogenicity of a Trivalent Salmonella Conjugate Vaccine to S. Typhi, S. Typhimurium, and S. Enteritidis.The Journal of infectious diseases · 2026Trial
- Detection and Characterization of Salmonella enterica Serotypes by Simple PCR Technologies.Methods in molecular biology (Clifton, N.J.) · 2027Article
- The Manipulation of Host Cells byInternational journal of molecular sciences · 2026Review
- Invasive Non-typhoidalInfectious diseases & clinical microbiology · 2026Article
- Pan genome clustering identifies a novel mosaic prophage specific to Salmonella Enteritidis lineage associated with the invasive disease in India.PLoS neglected tropical diseases · 2026Article
- Salmonella effector kinase SteC is activated by phosphorylation at Serine 379.PLoS pathogens · 2026Article
- Article
- Isolation and characterization of a novel lytic phage Artin targeting typhoidal and nontyphoidal Salmonella and evaluation of its antibacterial efficacy in food.Virology journal · 2026Article
- Advancements in CRISPR-Cas Systems for Genome Editing towards Eradication of Human Microbial Pathogens.Molecular biotechnology · 2026Review
- Salmonellosis Among Children Aged 0-14 Years in Greece over the Period 2005-2024: Descriptive Analysis of Surveillance Data from the Mandatory Notification System.Microorganisms · 2026Article
- Multivalent vaccines for invasiveInfection and immunity · 2026Review
- Infection strategies ofGut microbes reports · 2026Review
- Immunoinformatics-driven design of multi-epitope vaccine targeting antibiotic-resistant Salmonella typhimurium.PloS one · 2026Article
- Plasmid-driven clonal expansion of multidrug-resistant monophasicEmerging microbes & infections · 2025Article
- Assessing the Genomic Landscape of Salmonella enterica Isolated From Cattle Faeces on a Nigerian Farm.MicrobiologyOpen · 2025Article
244 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 5 institutions in 5 countries.
Funding
Abstract
Nontyphoidal Salmonella is a major cause of bloodstream infections worldwide, and HIV-infected persons and malaria-infected children are at increased risk for the disease. We conducted a systematic literature review to obtain age group-specific, population-based invasive nontyphoidal Salmonella (iNTS) incidence data. Data were categorized by HIV and malaria prevalence and then extrapolated by using 2010 population data. The case-fatality ratio (CFR) was determined by expert opinion consensus. We estimated that 3.4 (range 2.1-6.5) million cases of iNTS disease occur annually (overall incidence 49 cases [range 30-94] per 100,000 population). Africa, where infants, young children, and young adults are most affected, has the highest incidence (227 cases [range 152-341] per 100,000 population) and number of cases (1.9 [range 1.3-2.9] million cases). An iNTS CFR of 20% yielded 681,316 (range 415,164-1,301,520) deaths annually. iNTS disease is a major cause of illness and death globally, particularly in Africa. Improved understanding of the epidemiology of iNTS is needed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.