Evidence map›Paper›PMID 25860203›Full record

ArticleCritical care medicine2015

Goal-Directed Resuscitative Interventions During Pediatric Interfacility Transport.

Michael H Stroud, Ronald C Sanders, M Michele Moss, Janice E Sullivan, Parthak Prodhan, Maria Melguizo-Castro, Todd Nick

Abstract read
In one paragraph

Article in Critical care medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 15 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Michael H Stroud1Section of Critical Care Medicine, Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, AR. 2Section of Critical Care Medicine, Department of Pediatrics, University of Louisville, Louisville, KY. 3Division of Biostatistics, Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, AR.
Ronald C Sanders
M Michele Moss
Janice E Sullivan
Parthak Prodhan
Maria Melguizo-Castro
Todd Nick
University of Arkansas for Medical Sciences · USUniversity of Louisville · US

Funding

Goal-directed Resuscitative Interventions during Pediatric Inter-facility TranspoR21HD060171 · NICHD · ARKANSAS CHILDREN'S HOSPITAL RES INST · PI STROUD, MICHAEL HUGH · 2010 to 2011
$397k
NICHD NIH HHS 1R21HD060171-02ANICHD NIH HHS R21 HD060171
6 · The paper itself

Abstract

objectivesThis article reports results of the first National Institutes of Health-funded prospective interfacility transport study to determine the effect of goal-directed therapy administered by a specialized pediatric team to critically ill children with the systemic inflammatory response syndrome. We hypothesized that goal-directed therapy during interfacility transport would decrease hospital length of stay, prevent multiple organ dysfunction, and reduce subsequent ICU interventions.

designBefore-and-after intervention trial.

settingDuring interfacility transport of critically ill patients by a specialized pediatric transport team, back to a tertiary care children's hospital. PATIENTS: Before-and-after intervention trial.

designInterfacility pediatric transport patients, age 1 month to 17 years, with systemic inflammatory response syndrome.

interventionsProspective data were collected on all pediatric interfacility transport patients with systemic inflammatory response syndrome transported by the Angel One Transport team at Arkansas Children's Hospital. A 10-month data collection period was followed by institution of a goal-directed resuscitation protocol. Data were subsequently collected for 10 additional months followed by comparison of pre- and postintervention groups. All transport personnel underwent training with didactics and high-fidelity simulation until mastery with goal-directed resuscitation was achieved. MEASUREMENTS AND MAIN

resultsAll transport patients were screened for systemic inflammatory response syndrome using established variables and 235 (123 preintervention and 112 postintervention) were enrolled. Univariate analysis revealed shorter hospital stay (11 ± 15 d vs 7 ± 10 d; p = 0.02) and fewer required therapeutic ICU interventions in the postintervention group (Therapeutic Intervention Scoring System-28 Scores, 19.4 ± 6.8 vs 17.3 ± 6.6; p = 0.04). ICU stay and prevalence of organ dysfunction were not statistically different. Multivariable analysis showed a 1.6-day (95% CI, 1.3-2.03; p = 0.02) decrease in hospital stay in the postintervention group.

conclusionsThis study suggests that goal-directed therapy administered by a specialized pediatric transport team has the potential to impact the outcomes of critically ill children. Findings from this study should be confirmed across multiple institutions, but have the potential to impact the clinical outcomes of critically ill children with systemic inflammatory response syndrome.

Indexed as

ChildChild, PreschoolCritical IllnessFemaleHospitals, PediatricHumansLength of StayMaleMultiple Organ FailureNational Institutes of Health (U.S.)Patient Care PlanningPatient TransferProspective StudiesResuscitationSeverity of Illness IndexSystemic Inflammatory Response Syndrome

Identifiers

PMID25860203
PMCPMC4506208
OpenAlexW2313202475

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.