ArticlePhysics in medicine and biology2015
Quantitative methods for reconstructing tissue biomechanical properties in optical coherence elastography: a comparison study.
Article in Physics in medicine and biology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.
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Who cites it
51 citing papers in PubMed.
- Deep Learning-Based Inclusion Boundary Identification Using Wave Propagation in Optical Coherence Elastography.Journal of biophotonics · 2026Article
- Phantoms for use in optical coherence elastography.Journal of biomedical optics · 2026Review
- Quantifying age and spatial variations of bone marrow elasticity with noncontact optical coherence elastography.Journal of biomedical optics · 2025Article
- A-scan sequence transformers for palpation with optical coherence elastography.Biomedical optics express · 2025Article
- Ultrafast line-field holographic elastography with single excitation for corneal biomechanical characterization.Biomedical optics express · 2025Article
- Assessment of the Mechanical Properties of Soft Tissue Phantoms Using Impact Analysis.Sensors (Basel, Switzerland) · 2025Article
- Determinants of Human Corneal Mechanical Wave Dispersion for In Vivo Optical Coherence Elastography.Translational vision science & technology · 2025Article
- Shear Wave Elastography in Breast Cancer: Unveiling Correlations With Histopathological Grades and Subtypes.Cureus · 2024Article
- Recent advances in optical elastography and emerging opportunities in the basic sciences and translational medicine [Invited].Biomedical optics express · 2023Review
- Article
- Introduction to optical coherence elastography: tutorial.Journal of the Optical Society of America. A, Optics, image science, and vision · 2022Article
- Spatial Assessment of Heterogeneous Tissue Natural Frequency Using Micro-Force Optical Coherence Elastography.Frontiers in bioengineering and biotechnology · 2022Article
- Ultra-fast dynamic line-field optical coherence elastography.Optics letters · 2021Article
- Heartbeat optical coherence elastography: corneal biomechanics in vivo.Journal of biomedical optics · 2021Article
- Layer-specific ultrasound elastography using a multi-layered shear wave dispersion model for assessing the viscoelastic properties.Physics in medicine and biology · 2021Article
- A review of corneal biomechanics: Mechanisms for measurement and the implications for refractive surgery.Indian journal of ophthalmology · 2020Review
- Nearly-incompressible transverse isotropy (NITI) of cornea elasticity: model and experiments with acoustic micro-tapping OCE.Scientific reports · 2020Article
- Characterization of natural frequencies from nanoscale tissue oscillations using dynamic optical coherence elastography.Biomedical optics express · 2020Article
- Clinical Corneal Optical Coherence Elastography Measurement Precision: Effect of Heartbeat and Respiration.Translational vision science & technology · 2020Article
- Laser-induced elastic wave classification: thermoelastic versus ablative regimes for all-optical elastography applications.Journal of biomedical optics · 2020Article
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Authors and funding
12 authors.
Funding
Abstract
We present a systematic analysis of the accuracy of five different methods for extracting the biomechanical properties of soft samples using optical coherence elastography (OCE). OCE is an emerging noninvasive technique, which allows assessment of biomechanical properties of tissues with micrometer spatial resolution. However, in order to accurately extract biomechanical properties from OCE measurements, application of a proper mechanical model is required. In this study, we utilize tissue-mimicking phantoms with controlled elastic properties and investigate the feasibilities of four available methods for reconstructing elasticity (Young's modulus) based on OCE measurements of an air-pulse induced elastic wave. The approaches are based on the shear wave equation (SWE), the surface wave equation (SuWE), Rayleigh-Lamb frequency equation (RLFE), and finite element method (FEM), Elasticity values were compared with uniaxial mechanical testing. The results show that the RLFE and the FEM are more robust in quantitatively assessing elasticity than the other simplified models. This study provides a foundation and reference for reconstructing the biomechanical properties of tissues from OCE data, which is important for the further development of noninvasive elastography methods.
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