ArticleJournal of clinical and diagnostic research : JCDR2015
Evaluation of potential drug - drug interactions in general medicine ward of teaching hospital in southern India.
Article in Journal of clinical and diagnostic research : JCDR, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Potential drug-drug interactions in hospitalized patients with acute coronary syndrome at a tertiary care hospital in upper Egypt.Frontiers in pharmacology · 2026Article
- Factors associated with potential drug-drug interactions in psychiatric inpatients.European journal of hospital pharmacy : science and practice · 2024Article
- Hospitalized patients received furosemide undergoing acute kidney injury: the risk and prediction tool.European journal of medical research · 2023Article
- Article
- Prevalence of Potential Pharmacological Interactions in Patients Undergoing Systemic Chemotherapy in a Tertiary Hospital.Hospital pharmacy · 2022Article
- Determination of potential drug-drug interactions in prescription orders dispensed in a community pharmacy setting using MicromedexInternational journal of clinical pharmacy · 2022Observational
- The Prevalence of Potential Drug-Drug Interactions in CKD-A Retrospective Observational Study of Cerrahpasa Nephrology Unit.Medicina (Kaunas, Lithuania) · 2022Observational
- The Prevalence of Selected Potential Drug-Drug Interactions of Analgesic Drugs and Possible Methods of Preventing Them: Lessons Learned From the Analysis of the Real-World National Database of 38 Million Citizens of Poland.Frontiers in pharmacology · 2020Article
- Assessing Drug-Drug Interaction Potential among Patients Admitted to Surgery Departments in Three Palestinian Hospitals.BioMed research international · 2020Article
- Potential drug-drug interactions and associated factors among hospitalized cardiac patients at Jimma University Medical Center, Southwest Ethiopia.SAGE open medicine · 2019Article
- Are patients with a nasally placed feeding tube at risk of potential drug-drug interactions? A multicentre cross-sectional study.PloS one · 2019Article
- Prevalence and predictors of potential drug-drug interactions in patients of internal medicine wards of a tertiary care hospital in India.European journal of hospital pharmacy : science and practice · 2018Article
- Evaluation of Potential Drug-Drug Interactions with Antidepressants in Two Tertiary Care Hospitals.Journal of clinical and diagnostic research : JCDR · 2015Article
Corrections and comments
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Authors and funding
8 authors.
Funding
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Abstract
backgroundPolypharmacy is considered as one of the major risk factors in precipitation of drug-drug interactions (DDIs). Patient population at high risk include the elderly and patients with co morbidities as they are usually prescribed with more number of drugs. Critical evaluation of such prescriptions by pharmacist could result in identification and reduction of such problems.
objectiveThe study aims to assess the prevalence, severity and significance of potential DDI (pDDI) in general medicine wards of South Indian tertiary care teaching hospital. MATERIALS AND
methodA prospective observational study was conducted in a general medicine ward for a period of six months (September 2012 to February 2013). The socio-demographic, clinical characteristics and medication prescribed was documented in a specially designed form. Analysis was carried out to assess the prevalence, severity and significance of identified pDDIs using Micromedex. Descriptive and Univariate analysis were used to report the findings.
resultsA total of 404 case records reviewed, 78 (19.3%) patients had pDDIs. A total of 139 (34.4%) pDDIs were reported during the study period. Majority (53.95%, n=75) of the interactions were moderate in intensity and significant in nature (53.23%, n=74). Positive association between number of pDDIs and age was observed.
conclusionThe prevalence of pDDIs was 19.3% which is lesser then previously reported studies from India. Patient with more co-morbidities and elders were observed with more pDDIs. The study highlighted the need to effectively monitor and patients prevent pDDIs to improve patient safety.
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