ArticleJournal of clinical and diagnostic research : JCDR2015
Relationship between Antimicrobial Consumption and the Incidence of Antimicrobial Resistance in Escherichia coli and Klebsiella pneumoniae Isolates.
Article in Journal of clinical and diagnostic research : JCDR, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Effect of Increased Daily Water Intake in Premenopausal Women With Recurrent Urinary Tract Infections: A Randomized Clinical Trial.JAMA internal medicine · 2018Trial
- Effect of Tetracycline Dose and Treatment Mode on Selection of Resistant Coliform Bacteria in Nursery Pigs.Applied and environmental microbiology · 2017Trial
- Dynamic regression forecasting of carbapenem-resistant Klebsiella spp. based on carbapenem consumption with observed data from 2020 to 2023 and projections up to 2029 in a tertiary hospital in Alexandria, Egypt.BMC infectious diseases · 2026Article
- City or Suburb, Resistance Flows: Wastewater-BorneAntibiotics (Basel, Switzerland) · 2025Article
- Comparison of Cefepime with Piperacillin/Tazobactam Treatment in Patients with Hospital-Acquired Pneumonia.Antibiotics (Basel, Switzerland) · 2023Article
- Impact of Antibiotic Consumption on Antimicrobial Resistance to Invasive Hospital Pathogens.Antibiotics (Basel, Switzerland) · 2023Article
- Appraising epidemiology data and antimicrobial resistance of urinary tract infections in critically ill adult patients: a 7-year retrospective study in a referral Brazilian hospital.Sao Paulo medical journal = Revista paulista de medicina · 2023Article
- Retrospective Analysis of Sensitivity Characteristics ofInfection and drug resistance · 2023Article
- Role of risk perception and government regulation in reducing over-utilization of veterinary antibiotics: Evidence from hog farmers of China.One health (Amsterdam, Netherlands) · 2022Article
- Pharmacodynamic evaluation of piperacillin/tazobactam versus meropenem against extended-spectrum β-lactamase-producing and non-producing Escherichia coli clinical isolates in a hollow-fibre infection model.The Journal of antimicrobial chemotherapy · 2022Article
- Correlation Between Individual Child-Level Antibiotic Consumption and Antibiotic-Resistant Among CommensalInfection and drug resistance · 2022Article
- Disparities in antimicrobial consumption and resistance within a country: the case of beta-lactams in Argentina.Revista panamericana de salud publica = Pan American journal of public health · 2021Article
- Substandard Quality of the Antimicrobials Sold in the Street Markets in Haiti.Antibiotics (Basel, Switzerland) · 2020Article
- Effectiveness of alternative measures to reduce antimicrobial usage in pig production in four European countries.Porcine health management · 2020Article
- Article
- Development of Broth Microdilution MIC and Disk Diffusion Antimicrobial Susceptibility Test Quality Control Ranges for the Combination of Cefepime and the Novel β-Lactamase Inhibitor Enmetazobactam.Journal of clinical microbiology · 2019Article
- Prevalence of Drug-resistantIranian journal of public health · 2018Review
- Association between antibiotic consumption and the rate of carbapenem-resistant Gram-negative bacteria from China based on 153 tertiary hospitals data in 2014.Antimicrobial resistance and infection control · 2018Article
- Correlation between antibiotic consumption and resistance of bloodstream bacteria in a University Hospital in North Eastern Italy, 2008-2014.Infection · 2017Article
- Drug-resistance dynamics of Staphylococcus aureus between 2008 and 2014 at a tertiary teaching hospital, Jiangxi Province, China.BMC infectious diseases · 2017Article
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Authors and funding
4 authors.
Funding
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Abstract
introductionGram negative organisms are one of the major causes of nosocomial diseases. Development of resistance to antibiotics by these organisms increases their risk in clinical treatment of patients. It also affects morbidity and mortality hence needs to be monitored and controlled.
aimThe aim of the present study was to analyse the correlation between consumption of parenteral antibiotics and the rates of antimicrobial resistance among the Escherichia coli and Klebsiella pneumoniae isolates collected during Dec 2010 - Jun 2013 from JIPMER hospital. MATERIALS AND
methodsConsumption data of parenteral antibiotics in J01 category of Anatomical Therapeutic Chemical (ATC) in JIPMER was obtained and expressed in Defined Daily Doses (DDD) per 1000 inhabitants. Valid consumption and resistance data during the period Dec 2010 to Jun 2013 were obtained at 6 month intervals and were correlated to draw a relationship between antimicrobial consumption and its impact on drug resistance for Escherichia coli and Klebsiella pneumoniae.
resultsEscherichia coli isolates showed high resistance for increased use of gentamycin and ciprofloxacin. Increase in antibiotic consumption increases the resistance for Escherichia coli except for amikacin. Among the Klebsiella isolates, meropenem and gentamycin showed high correlations followed by ceftazidime, amikacin, ceftriaxone and ciprofloxacin.
conclusionIn summary, a statistically significant association was noticed between consumption of the studied antimicrobials and resistance of Escherichia coli isolates, except for amikacin and ceftazidime. In the case of Klebsiella pneumoniae, there was a statistically significant association between the resistance rates and consumption of gentamycin, ceftazidime and meropenem. Further, a linear relationship was noted between antimicrobial consumption and resistant isolates of Escherichia coli and Klebsiella pneumoniae, except for Escherichia coli resistance to amikacin.
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