ReviewIranian journal of basic medical sciences2014
Black cumin (Nigella sativa) and its constituent (thymoquinone): a review on antimicrobial effects.
Review in Iranian journal of basic medical sciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04347382 (The Role of Honey and Nigella Sativa in the Management of COVID-19; A Randomized Controlled, Open-label, Add-on Trial in Pakistan), which is not on this map. Cited by 101 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Role of Honey and Nigella Sativa in the Management of COVID-19; A Randomized Controlled, Open-label, Add-on Trial in Pakistan
Who cites it
101 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effect ofCurrent medicinal chemistry · 2025Pooled it
- Efficacy of Persian medicine herbal formulations (capsules and decoction) compared to standard care in patients with COVID-19, a multicenter open-labeled, randomized, controlled clinical trial.Phytotherapy research : PTR · 2021Trial
- Chemical Composition and Functional Effects of Oilseed Cakes on Redox Balance, Immune Function, Growth Performance, and Carcass Characteristics in Swine Production: A Review.Animals : an open access journal from MDPI · 2026Review
- From Natural Product to Topical Antimicrobial Candidate: EvaluatingPharmaceuticals (Basel, Switzerland) · 2026Article
- Exploring the Multifaceted Phytochemical Profile ofPharmaceuticals (Basel, Switzerland) · 2026Article
- ATR-FTIR spectroscopy combined with chemometrics reveals molecular alterations and anticancer effects of Nigella sativa extract in human colon cancer cells.Scientific reports · 2026Article
- The Effect of the Extraction Method on the Content of Bioactive Compounds and the Biological Activity ofMolecules (Basel, Switzerland) · 2025Article
- Analytical Determination of the Lipid Fraction ofMolecules (Basel, Switzerland) · 2025Article
- Multifunctional Roles of Medicinal Plants in the Meat Industry: Antioxidant, Antimicrobial, and Color Preservation Perspectives.Plants (Basel, Switzerland) · 2025Review
- Functional, Nutraceutical, and Pharmacological Properties of Black Seed.Food science & nutrition · 2025Review
- A voltammetric approach for the quantification of thymoquinone in Nigella Sativa products.Scientific reports · 2025Article
- Article
- Deciphering the anticancer potential of thymoquinone: in-depth exploration of the potent flavonoid from Nigella sativa.Molecular biology reports · 2025Review
- Carbapenem resistance and antibacterial potential of the Libyan endemic plant Arbutus pavarii against metallo-β-lactamase-producing Gram-negative bacteria.Access microbiology · 2025Article
- Article
- Therapeutic efficacy ofFrontiers in nutrition · 2025Review
- Diversity of Ethiopian Black Cumin (Biochemistry research international · 2025Article
- An Overview of Possible Beneficial Effects of Black Seeds (Infectious disorders drug targets · 2025Review
- A Comprehensive Analysis of Liposomal-Based Nanocarriers for Treating Skin and Soft Tissue Infection.Current drug delivery · 2025Review
- Antibacterial and Anti-biofilm Effects of Thymoquinone Against Carbapenem-Resistant UropathogenicIndian journal of microbiology · 2024Article
41 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nigella sativa seeds have wide therapeutic effects and have been reported to have significant effects against many ailments such as skin diseases, jaundice, gastrointestinal problems, anorexia, conjunctivitis, dyspepsia, rheumatism, diabetes, hypertension, intrinsic hemorrhage, paralysis, amenorrhea, anorexia, asthma, cough, bronchitis, headache, fever, influenza and eczema. Thymoquinone (TQ) is one of the most active constituent and has different beneficial properties. Focus on antimicrobial effects, different extracts of N. sativa as well as TQ, have a broad antimicrobial spectrum including Gram-negative, Gram-positive bacteria, viruses, parasites, schistosoma and fungi. The effectiveness of N. sativa seeds and TQ is variable and depends on species of target microorganisms. The present review paper tries to describe all antimicrobial activities that have been carried out by various researchers.
Indexed as
Identifiers
25859296PMC4387228What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.