Evidence map›Paper›PMID 25859154›Full record

ArticleTropical medicine and health2015

A Prospective Hospital-based Surveillance to Estimate Rotavirus Disease Burden in Bhutanese Children under 5 Years of Age.

Sonam Wangchuk, Tshering Dorji, Tsheten, Karchung Tshering, Sangay Zangmo, Kunzang Pem Tshering, Tandin Dorji, Akira Nishizono, Kamruddin Ahmed

Abstract read
In one paragraph

Article in Tropical medicine and health, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sonam WangchukPublic Health Laboratory, Department of Public Health, Ministry of Health, Royal Government of Bhutan , Thimphu, Bhutan.
Tshering DorjiPublic Health Laboratory, Department of Public Health, Ministry of Health, Royal Government of Bhutan , Thimphu, Bhutan.
TshetenPublic Health Laboratory, Department of Public Health, Ministry of Health, Royal Government of Bhutan , Thimphu, Bhutan.
Karchung TsheringPublic Health Laboratory, Department of Public Health, Ministry of Health, Royal Government of Bhutan , Thimphu, Bhutan.
Sangay ZangmoPublic Health Laboratory, Department of Public Health, Ministry of Health, Royal Government of Bhutan , Thimphu, Bhutan.
Kunzang Pem TsheringDepartment of Pediatrics, Jigme Dorji Wangchuk National Referral Hospital , Thimphu, Bhutan.
Tandin DorjiCommunicable Disease Division, Department of Public Health, Ministry of Health, Royal Government of Bhutan , Thimphu, Bhutan.
Akira NishizonoDepartment of Microbiology, Faculty of Medicine, Oita University , Yufu, Oita, Japan.
Kamruddin AhmedDepartment of Microbiology, Faculty of Medicine, Oita University , Yufu, Oita, Japan ; Research Promotion Institute, Oita University , Yufu, Oita, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As part of efforts to develop an informed policy for rotavirus vaccination, this prospective study was conducted to estimate the burden of rotavirus diarrhea among children less than 5 years old attended to the Department of Pediatrics, Jigme Dorji Wangchuk National Referral Hospital (JDWNRH), Thimphu, Bhutan. The duration of the study was three years, extending from February 2010 through December 2012. We estimated the frequency of hospitalization in the pediatric ward and dehydration treatment unit (DTU) for diarrhea and the number of events attributable to rotavirus infection among children under 5 years of age. During the study period, a total of 284 children (1 in 45) were hospitalized in the pediatric ward, and 2,220 (1 in 6) in the DTU with diarrhea among children residing in the Thimphu district. Group A rotavirus was detected in 32.5% and 18.8% of the stool samples from children hospitalized in the pediatric ward, respectively. Overall, 22.3% of the stool samples were rotavirus-positive, and the majority (90.8%) of them was detected in children under 2 years of age. From this study, we estimated that the annual incidence of hospitalization in the pediatric ward and DTU due to rotavirus diarrhea was 2.4/1000 (95% CI 1.7-3.4) and 10.8/1000 (95% CI 9.1-12.7) children, respectively. This study revealed that rotavirus is a major cause of diarrhea in Bhutanese children in Thimphu district and since no study has been performed previously, represents an important finding for policy discussions regarding the adoption of a rotavirus vaccine in Bhutan.

Indexed as

BhutanBurdenChildrenRotavirusVaccine

Identifiers

PMID25859154
PMCPMC4361340

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.