ReviewTropical medicine and health2015
The role of carbohydrates in infection strategies of enteric pathogens.
Review in Tropical medicine and health, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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Who cites it
38 citing papers in PubMed, 90 citations in OpenAlex.
- Selective antimicrobial potential of fucoidans against the pathogenFrontiers in microbiology · 2026Article
- Atomic force microscopy at the forefront: unveiling foodborne viruses with biophysical tools.Npj viruses · 2025Review
- Identification of nine mammal monosaccharides by solid-state nanopores.Scientific reports · 2024Article
- Antibiotic alters host's gut microbiota, fertility, and antimicrobial peptide gene expression vis-à-vis ampicillin treatment on model organism Drosophila melanogaster.International microbiology : the official journal of the Spanish Society for Microbiology · 2024Article
- Lectin histochemistry in the small intestines of piglets naturally infected with porcine epidemic diarrhea virus.Journal of veterinary science · 2024Article
- Effect of in ovo feeding of xylobiose and xylotriose on plasma immunoglobulin, cecal metabolites production, microbial ecology, and metabolic pathways in broiler chickens.Journal of animal science and biotechnology · 2024Article
- Blood Group Variations in COVID-19 Convalescent Plasma and Regular Blood Donors: A Comparative Analysis in the Serbian Population.Microorganisms · 2024Article
- Article
- Galactoside-Based Molecule Enhanced Antimicrobial Activity through Acyl Moiety Incorporation: Synthesis and In Silico Exploration for Therapeutic Target.Pharmaceuticals (Basel, Switzerland) · 2023Article
- Structure-Based Neural Network Protein-Carbohydrate Interaction Predictions at the Residue Level.bioRxiv : the preprint server for biology · 2023Article
- Digital microfluidics-engaged automated enzymatic degradation and synthesis of oligosaccharides.Frontiers in bioengineering and biotechnology · 2023Article
- Structure-based neural network protein-carbohydrate interaction predictions at the residue level.Frontiers in bioinformatics · 2023Article
- Xylan Prebiotics and the Gut Microbiome Promote Health and Wellbeing: Potential Novel Roles for Pentosan Polysulfate.Pharmaceuticals (Basel, Switzerland) · 2022Review
- Characterization and Antibacterial Evaluation of Biodegradable Mannose-Conjugated Fe-MIL-88NHPolymers · 2022Article
- The correlation between non-O blood group type and recurrent catheter-associated urinary tract infections in critically ill patients: A retrospective study.The Journal of international medical research · 2022Article
- N-Acetylglucosamine Sensing and Metabolic Engineering for Attenuating Human and Plant Pathogens.Bioengineering (Basel, Switzerland) · 2022Review
- Glycopolymer-Wrapped Carbon Nanotubes Show Distinct Interaction of Carbohydrates With Lectins.Frontiers in chemistry · 2022Article
- Mucus and Mucins: The Underappreciated Host Defence System.Frontiers in cellular and infection microbiology · 2022Review
- Synthesis of Ribose-Coated Copper-Based Metal-Organic Framework for Enhanced Antibacterial Potential of Chloramphenicol against Multi-Drug Resistant Bacteria.Antibiotics (Basel, Switzerland) · 2021Article
- Antiparasitic Effects of Sulfated Polysaccharides from Marine Hydrobionts.Marine drugs · 2021Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Enteric pathogens cause considerable public health concerns worldwide including tropical regions. Here, we review the roles of carbohydrates in the infection strategies of various enteric pathogens including viruses, bacteria and protozoa, which infect the epithelial lining of the human and animal intestine. At host cell entry, enteric viruses, including norovirus, recognize mainly histo-blood group antigens. At the initial step of bacterial infections, carbohydrates also function as receptors for attachment. Here, we describe the function of carbohydrates in infection by Salmonella enterica and several bacterial species that produce a variety of fimbrial adhesions. During invasion by enteropathogenic protozoa, apicomplexan parasites utilize sialic acids or sulfated glycans. Carbohydrates serve as receptors for infection by these microbes; however, their usage of carbohydrates varies depending on the microbe. On the surface of the mucosal tissues of the gastrointestinal tract, various carbohydrate moieties are present and play a crucial role in infection, representing the site of infection or route of access for most microbes. During the infection and/or invasion process of the microbes, carbohydrates function as receptors for various microbes, but they can also function as a barrier to infection. One approach to develop effective prophylactic and therapeutic antimicrobial agents is to modify the drug structure. Another approach is to modify the mode of inhibition of infection depending on the individual pathogen by using and mimicking the interactions with carbohydrates. In addition, similarities in mode of infection may also be utilized. Our findings will be useful in the development of new drugs for the treatment of enteric pathogens.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.