Evidence map›Paper›PMID 25858140›Full record

ReviewVirology2015

Viruses and the autophagy pathway.

William T Jackson

Abstract readReview
In one paragraph

Review in Virology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 138 papers.

0numbers the graph read from it
0cells of the map it votes in
138citing papers in PubMed
14.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

138 citing papers in PubMed, 201 citations in OpenAlex.

  1. Article
  2. Review
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  7. Article
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  9. Article
  10. Review
  11. Review
  12. Interaction between coronaviruses and the autophagic response.Frontiers in cellular and infection microbiology · 2024
    Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Exosome-Autophagy Crosstalk in Enveloped Virus Infection.International journal of molecular sciences · 2023
    Review
  18. Article
  19. Review
  20. Review

78 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

William T JacksonDepartment of Microbiology and Molecular Genetics, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53211, United States. Electronic address: wjackson@mcw.edu.
Medical College of Wisconsin · US

Funding

The roles of acidic autophagosomes in production of infectious poliovirusR01AI104928 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI JACKSON, WILLIAM T · 2014 to 2023
$3.8M
NIAID NIH HHS R01 AI104928
6 · The paper itself

Abstract

Studies of the cellular autophagy pathway have exploded over the past twenty years. Now appreciated as a constitutive degradative mechanism that promotes cellular homeostasis, autophagy is also required for a variety of developmental processes, cellular stress responses, and immune pathways. Autophagy certainly acts as both an anti-viral and pro-viral pathway, and the roles of autophagy depend on the virus, the cell type, and the cellular environment. The goal of this review is to summarize, in brief, what we know so far about the relationship between autophagy and viruses, particularly for those who are not familiar with the field. With a massive amount of relevant published data, it is simply not possible to be comprehensive, or to provide a complete "parade of viruses", and apologies are offered to researchers whose work is not described herein. Rather, this review is organized around general themes regarding the relationship between autophagy and animal viruses.

Indexed as

AutophagyHost-Parasite InteractionsVirus Physiological PhenomenaVirus ReleaseHumansVirusesAmphisomeAutophagyAWOLBeclin 1EndosomeIFNSNAREVirus

Identifiers

PMID25858140
PMCPMC5917100
OpenAlexW2001790634

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.