Evidence map›Paper›PMID 25857904›Full record

ArticleJournal of the American College of Cardiology2015

Readmissions after carotid artery revascularization in the Medicare population.

Mohammed Salim Al-Damluji, Kumar Dharmarajan, Weiwei Zhang, Lori L Geary, Erik Stilp, Alan Dardik, Carlos Mena-Hurtado, Jeptha P Curtis

Abstract readMulticenter Study
In one paragraph

Article in Journal of the American College of Cardiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Mohammed Salim Al-DamlujiDepartment of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut.
Kumar DharmarajanCenter for Outcome Research and Evaluation, Yale University, New Haven, Connecticut; Division of Cardiology, Columbia University Medical Center, New York, New York.
Weiwei ZhangCenter for Outcome Research and Evaluation, Yale University, New Haven, Connecticut.
Lori L GearyCenter for Outcome Research and Evaluation, Yale University, New Haven, Connecticut.
Erik StilpDepartment of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut; Cardiovascular Division, Department of Medicine, Yale University School of Medicine, New Haven, Connecticut.
Alan DardikYale University Vascular Biology and Therapeutics Program, New Haven, Connecticut; Department of Surgery, Yale University School of Medicine, New Haven, Connecticut; Veterans Affairs Connecticut Healthcare System, West Haven, Connecticut.
Carlos Mena-HurtadoDepartment of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut; Cardiovascular Division, Department of Medicine, Yale University School of Medicine, New Haven, Connecticut.
Jeptha P CurtisDepartment of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut; Center for Outcome Research and Evaluation, Yale University, New Haven, Connecticut; Cardiovascular Division, Department of Medicine, Yale University School of Medicine, New Haven, Connecticut. Electronic address: jeptha.curtis@yale.edu.

Funding

Center for Cardiovascular Outcomes Research at Yale UniversityU01HL105270 · NHLBI · YALE UNIVERSITY · PI CURTIS, JEPTHA PELHAM, KRUMHOLZ, HARLAN MARC · 2010 to 2013
$5.8M
Geriatric Conditions and Readmission after Acute Myocardial InfarctionK23AG048331 · NIA · YALE UNIVERSITY · PI DHARMARAJAN, KUMAR · 2014 to 2017
$692k
NHLBI NIH HHS U01 HL105270NHLBI NIH HHS U01 HL105270-03NIA NIH HHS K23 AG048331
6 · The paper itself

Abstract

backgroundIn appropriately selected patients with severe carotid stenosis, carotid revascularization reduces ischemic stroke. Prior clinical research has focused on the efficacy and safety of carotid revascularization, but few investigators have considered readmission as a clinically important outcome.

objectivesThe aims of this study were to examine frequency, timing, and diagnoses of 30-day readmission following carotid revascularization; to assess differences in 30-day readmission between patients undergoing carotid endarterectomy (CEA) and carotid artery stenting (CAS); to describe hospital variation in risk-standardized readmission rates (RSRR); and to examine whether hospital variation in the choice of procedure (CEA vs. CAS) is associated with differences in RSRRs.

methodsWe used Medicare fee-for-service administrative claims data to identify acute care hospitalizations for CEA and CAS from 2009 to 2011. We calculated crude 30-day all-cause hospital readmissions following carotid revascularization. To assess differences in readmission after CAS compared with CEA, we used Kaplan-Meier survival curves and fitted mixed-effects logistic regression. We estimated hospital RSRRs using hierarchical generalized logistic regression. We stratified hospitals into 5 groups by their proportional CAS use and compared hospital group median RSRRs.

resultsOf 180,059 revascularizations from 2,287 hospitals, CEA and CAS were performed in 81.5% and 18.5% of cases, respectively. The unadjusted 30-day readmission rate following carotid revascularization was 9.6%. Readmission risk after CAS was greater than that after CEA. There was modest hospital-level variation in 30-day RSRRs (median: 9.5%; range 7.5% to 12.5%). Variation in proportional use of CAS was not associated with differences in hospital RSRR (range of median RSRR across hospital groups 9.49% to 9.55%; p = 0.771).

conclusionsAlmost 10% of Medicare patients undergoing carotid revascularization were readmitted within 30 days of discharge. Compared with CEA, CAS was associated with a greater readmission risk. However, hospitals' RSRR did not differ by their proportional CAS use.

Indexed as

Population SurveillanceAgedAged, 80 and overCarotid StenosisEndarterectomy, CarotidFemaleHumansMaleMedicarePatient ReadmissionTreatment OutcomeUnited Statescarotid artery stenosiscarotid artery stentingcarotid endarterectomyhospital readmission

Identifiers

PMID25857904
PMCPMC4403264

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.