Evidence map›Paper›PMID 25857761›Full record

ArticleAJNR. American journal of neuroradiology2015

Application of a Novel Brain Arteriovenous Malformation Endovascular Grading Scale for Transarterial Embolization.

D L Bell, T M Leslie-Mazwi, A J Yoo, J D Rabinov, W E Butler, J E Bell, J A Hirsch

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Article in AJNR. American journal of neuroradiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Single-center experience with endovascular treatment of cerebral arteriovenous malformations with intent to cure in pediatric patients.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2022
    Article
  4. Observational
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

D L BellFrom the Department of Radiology, Neuroendovascular Program (D.L.B., A.J.Y., J.D.R., J.A.H.) Harvard Medical School (D.L.B., T.M.L.-M., J.D.R., W.E.B., J.A.H.), Boston, Massachusetts d.l.bell.jr@gmail.com.
T M Leslie-MazwiDepartment of Neurology and Radiology, Neurocritical Care and Neuroendovascular Program (T.M.L.-M.) Harvard Medical School (D.L.B., T.M.L.-M., J.D.R., W.E.B., J.A.H.), Boston, Massachusetts.
A J YooFrom the Department of Radiology, Neuroendovascular Program (D.L.B., A.J.Y., J.D.R., J.A.H.) Texas Stroke Institute (A.J.Y.), Plano, Texas.
J D RabinovFrom the Department of Radiology, Neuroendovascular Program (D.L.B., A.J.Y., J.D.R., J.A.H.) Harvard Medical School (D.L.B., T.M.L.-M., J.D.R., W.E.B., J.A.H.), Boston, Massachusetts.
W E ButlerDepartment of Neurosurgery, Vascular Center (W.E.B.), Massachusetts General Hospital, Boston, Massachusetts Harvard Medical School (D.L.B., T.M.L.-M., J.D.R., W.E.B., J.A.H.), Boston, Massachusetts.
J E BellFrom the Department of Radiology, Neuroendovascular Program (D.L.B., A.J.Y., J.D.R., J.A.H.).
J A HirschFrom the Department of Radiology, Neuroendovascular Program (D.L.B., A.J.Y., J.D.R., J.A.H.) Harvard Medical School (D.L.B., T.M.L.-M., J.D.R., W.E.B., J.A.H.), Boston, Massachusetts.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeThe advent of modern neuroendovascular techniques has highlighted the need for a simple, effective, and reliable brain arteriovenous malformation endovascular grading scale. A novel scale of this type has recently been described. It incorporates the number of feeding arteries, eloquence, and the presence of an arteriovenous fistula component. Our aim is to assess the validity of this grading scale. MATERIALS AND

methodsWe retrospectively reviewed all suspected brain arteriovenous malformations at Massachusetts General Hospital from 2005 to 2013, identifying 126 patients who met the inclusion criteria. Spearman correlations between endovascular and Spetzler-Martin grading scales and long-term outcomes were performed. Median endovascular grades were compared between treatment modalities and endovascular outcomes. Binary regression analysis was performed with major endovascular complications as a dichotomized dependent variable. Intraclass correlation coefficients were calculated for interobserver reliability of the endovascular grading scale.

resultsA significant Spearman correlation between the endovascular grade and the Spetzler-Martin grade was demonstrated (ρ = 0.5, P < .01). Differences in the median endovascular grades between the endovascular cure (median = 2) and endovascular complication groups (median = 4) (P < .05) and between the endovascular cure and successful multimodal treatment groups (median = 3) (P < .05) were demonstrated. The endovascular grade was the only independent predictor of complications (OR = 0.5, P < .01). The intraclass correlation coefficient of the endovascular grade was 0.71 (P < .01).

conclusionsValidation of a brain arteriovenous malformation endovascular grading scale demonstrated that endovascular grades of ≤II were associated with endovascular cure, while endovascular grades of ≤III were associated with multimodal cure or significant lesion reduction and favorable outcome. The endovascular grade provides useful information to refine risk stratification for endovascular and multimodal treatment.

Indexed as

AdultAgedArteriovenous FistulaEmbolization, TherapeuticEndovascular ProceduresFemaleHumansIntracranial Arteriovenous MalformationsMaleMiddle AgedReproducibility of ResultsSeverity of Illness Index

Identifiers

PMID25857761
PMCPMC7965262

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.