Evidence map›Paper›PMID 25857741›Full record

ArticleInternational wound journal2016

Immunomodulator 'mushroom beta glucan' induces Wnt/β catenin signalling and improves wound recovery in tilapia and rat skin: a histopathological study.

Chien-Mei Hsiao, Yu-Sheng Wu, Fan-Hua Nan, Shih-Ling Huang, Lynette Chen, Shiu-Nan Chen

Open access · bronzeAbstract read
In one paragraph

Article in International wound journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Chien-Mei HsiaoInstitute of Fisheries Science, National Taiwan University, Taipei, Taiwan.
Yu-Sheng WuInstitute of Fisheries Science, National Taiwan University, Taipei, Taiwan.
Fan-Hua NanDepartment of Aquaculture, National Taiwan Ocean University, Keelung, Taiwan.
Shih-Ling HuangFreshwater Aquaculture Research Center, Fisheries Research Institute, Council of Agriculture, Changhua, Taiwan.
Lynette ChenOregon Health and Science University Hospital Oregon, Oregon, OR, USA.
Shiu-Nan ChenInstitute of Fisheries Science, National Taiwan University, Taipei, Taiwan.
National Taiwan University · TWCouncil of Agriculture · TWNational Taiwan Ocean University · TWOregon Health and Science University Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study aims to investigate the effects of mushroom beta glucan (MBG) on wound recovery in partial hepatectomy (PH) in Nile tilapia (Oreochromis niloticus) and in rat skin wound healing examination. Following PH, we focussed on the effects on liver repair ability using in vitro and in vivo tests. In vitro, we examined whether the MBG has an impact on liver cell proliferation, mainly through 3-(4,5-dimethylthiazolyl-2)-2,5-diphenyltetrazolium bromide (MTT) assays and bromodeoxyuridine (BrdU) cell proliferation assay detection method. Results showed that MBG treatment was remarkable in enhancing cell proliferation of hepatocytes and in maintaining the cellular viability. Immunohistochemical staining to analyse Wnt/β-catenin signalling also showed that MBG has the effect of promoting cell proliferation of liver tissues after PH surgery.

Indexed as

Wound HealingAgaricalesAnimalsbeta Cateninbeta-GlucansImmunologic FactorsRatsSkinTilapiaWnt Signaling Pathwaybeta Cateninbeta-GlucansImmunologic FactorsGrowth factorHistopathologyImmunomodulatorWnt/β-catenin signallingWound recovery

Identifiers

PMID25857741
PMCPMC7949842
OpenAlexW1492838084

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.