ReviewInternational journal of oral science2015
Diabetes mellitus related bone metabolism and periodontal disease.
Review in International journal of oral science, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 134 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
134 citing papers in PubMed, 2 syntheses or guidelines pooled it, 301 citations in OpenAlex.
- Updates from the Evidence Base Examining Association between Periodontal Disease and Type 2 Diabetes Mellitus: Current Status and Clinical Relevance.Current diabetes reports · 2019Pooled it
- Dental implant treatment for renal failure patients on dialysis: a clinical guideline.International journal of oral science · 2017Guideline
- Trial
- A logic-gated nanoplatform spatiotemporally orchestrates immunometabolic reprogramming and osteogenesis for diabetic periodontal regeneration.Bioactive materials · 2027Article
- Hierarchical Nanoplatform Integrating Oxidative-Acidic Microenvironment Remodeling and Bone Homeostasis Modulation for Diabetic Bone Defect Therapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Hypoglycemic and tissue protective effects of mangosteen (Garcinia mangostana L.) on diabetes associated periodontal tissue alterations.Odontology · 2026Article
- Radiographic assessment of the relationship between alveolar bone loss and overhanging margins of posterior dental restorations in diabetic patients: a retrospective study.Oral radiology · 2026Article
- Attitudes About Administrative Burdens for Beneficiaries and Dental Care Providers in Medicaid.Journal of public health dentistry · 2026Article
- The Burden and Projections for 2036 of Periodontal Diseases in Asia From 1990 to 2021.International dental journal · 2026Article
- Hyperglycemia and systemic inflammation differentially shape immune dysregulation, tissue destruction, and microbiota in experimental periodontitis and peri-implantitis in diabetic mice.Frontiers in immunology · 2026Article
- Versatile smart hydrogels for spatiotemporal drug delivery to orchestrate diabetic bone regeneration.Bioactive materials · 2026Article
- Recipient Periodic Fasting Promotes Osteogenesis of Implanted Mesenchymal Stromal Cell Aggregates and Safeguards Diabetic Mandibular Bone Regeneration.Stem cell reviews and reports · 2025Article
- Periodontal markers predict glycemic control in diabetic patients a ten year retrospective analysis.Scientific reports · 2025Article
- Epidemiological Data on Periodontitis in a Sample of the Bulgarian Population: A Retrospective Study.Cureus · 2025Article
- Effect of Diabetes Mellitus on Survival and Complication Rates of Tooth-Supported Fixed Dental Prostheses (FDPs): Long-Term Clinical Evaluation.Journal of clinical medicine · 2025Article
- The Adjunctive Role of Antimicrobial Photodynamic Therapy to Non-Surgical Treatment in Patients with Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis.Healthcare (Basel, Switzerland) · 2025Review
- Periodontal disease and the incident risk of diabetes mellitus in Japanese men and women: a 12-year cohort study.Diabetology international · 2025Article
- Iron dysregulation, ferroptosis, and oxidative stress in diabetic osteoporosis: Mechanisms, bone metabolism disruption, and therapeutic strategies.World journal of diabetes · 2025Review
- Data-driven diabetes mellitus prediction and management: a comparative evaluation of decision tree classifier and artificial neural network models along with statistical analysis.Scientific reports · 2025Article
- Association Between Diabetes and Vertical Bone Defects in Periodontitis Using Cone Beam Computed Tomography: A Cross-Sectional Study in the Eastern Province, Saudi Arabia.Clinics and practice · 2025Article
74 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
Abstract
Diabetes mellitus and periodontal disease are chronic diseases affecting a large number of populations worldwide. Changed bone metabolism is one of the important long-term complications associated with diabetes mellitus. Alveolar bone loss is one of the main outcomes of periodontitis, and diabetes is among the primary risk factors for periodontal disease. In this review, we summarise the adverse effects of diabetes on the periodontium in periodontitis subjects, focusing on alveolar bone loss. Bone remodelling begins with osteoclasts resorbing bone, followed by new bone formation by osteoblasts in the resorption lacunae. Therefore, we discuss the potential mechanism of diabetes-enhanced bone loss in relation to osteoblasts and osteoclasts.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.