ArticleJournal of veterinary internal medicine
Acute phase proteins in racehorses with inflammatory airway disease.
Article in Journal of veterinary internal medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 41 citations in OpenAlex.
- Biomarkers of equine asthma: A review of the current literature.Veterinary research communications · 2026Review
- How Inflamed Is the Horse in Training? Insights into Exercise-Induced Acute Phase Response in Endurance Horses.International journal of molecular sciences · 2026Review
- Acute phase proteins levels in horses, after a single carbohydrate overload, associated with cecal alkalinization.Frontiers in veterinary science · 2023Article
- Changes in Acute Phase Response Biomarkers in Racing Endurance Horses.Animals : an open access journal from MDPI · 2022Article
- Neutrophil Extracellular Traps Are Found in Bronchoalveolar Lavage Fluids of Horses With Severe Asthma and Correlate With Asthma Severity.Frontiers in immunology · 2022Article
- Comparison of the proteomes in sera between healthy Thoroughbreds and Thoroughbreds with respiratory disease associated with transport using mass spectrometry-based proteomics.Journal of equine science · 2021Article
- Reference intervals of acute phase proteins in healthy Andalusian donkeys and response to experimentally induced endotoxemia.Journal of veterinary internal medicine · 2021Article
- Equine Inflammatory Markers in the Twenty-First Century: A Focus on Serum Amyloid A.The Veterinary clinics of North America. Equine practice · 2020Review
- Equine Asthma: Current Understanding and Future Directions.Frontiers in veterinary science · 2020Review
- Conflict Between Direct Experience and Research-Based Evidence Is a Key Challenge to Evidence-Based Respiratory Medicine on British Racing Yards.Frontiers in veterinary science · 2020Article
- Investigation of blood biomarkers for the diagnosis of mild to moderate asthma in horses.Journal of veterinary internal medicine · 2019Article
- Serum amyloid A in equine health and disease.Equine veterinary journal · 2019Review
- Clinical findings and outcome predictors for multinodular pulmonary fibrosis in horses: 46 cases (2009-2019).Journal of veterinary internal medicineArticle
- Serum Surfactant Protein D and Haptoglobin as Potential Biomarkers for Inflammatory Airway Disease in Horses.Journal of veterinary internal medicineArticle
- Inflammatory Airway Disease of Horses--Revised Consensus Statement.Journal of veterinary internal medicineArticle
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSystemic inflammation is observed in horses with heaves and could also be present in horses with a lesser degree of pulmonary inflammation. HYPOTHESIS/
objectivesIt was hypothesized that racehorses with inflammatory airway disease (IAD) have increased concentration of circulating acute phase proteins. The objective of this study was to compare serum acute phase proteins of racehorses with and without lower airway inflammation. ANIMALS: Serum from 21 client-owned Standardbred racehorses with exercise intolerance and lower airway inflammation and serum from 10 client-owned Standardbred racehorses with exercise intolerance without lower airway inflammation.
methodsIn a case-control study, serum samples from previously characterized horses presented for exercise intolerance with or without lower airway inflammation based on bronchoalveolar lavage fluid cytology were analyzed for serum amyloid A protein (SAA), C-reactive protein (CRP), and haptoglobin using commercial ELISAs.
resultsThere was no significant differences between groups for SAA (non-IAD versus IAD, median (range): 3.47 (0.06-34.94) versus 6.33 (0.06-80) μg/mL, P = .49), CRP (10.87 (2.05-29.03) versus 4.63 (0.02-31.81) μg/mL, P = .23) or haptoglobin (900.36 (607.99-2018.84) versus 749.54 (530.81-1076.95) μg/mL, P = .09). CONCLUSIONS AND CLINICAL IMPORTANCE: In this population of poorly performing racehorses in training, serum SAA, CRP, and haptoglobin were not helpful in distinguishing between horses with IAD from horses with exercise intolerance from other causes.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.