Evidence map›Paper›PMID 25856681›Full record

ArticleMedicine and science in sports and exercise2015

Pain Response after Maximal Aerobic Exercise in Adolescents across Weight Status.

Stacy Stolzman, Michael Danduran, Sandra K Hunter, Marie Hoeger Bement

Registry-linked trialAbstract read
In one paragraph

Article in Medicine and science in sports and exercise, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07182006 (Movement as Medicine), which is not on this map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07182006 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Movement as Medicine: Can a Single Bout of Aerobic Exercise Elicit Exercise-induced Hypoalgesia in Youth With and Without Chronic Pain Syndromes?

TypeinterventionalSponsorBoston Children's HospitalRan2026 to 2027Enrolled66ConditionsChronic Pain, Child, AdolescentArmsAerobic Exercise
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Does Exercise Decrease Pain via Conditioned Pain Modulation in Adolescents?Pediatric physical therapy : the official publication of the Section on Pediatrics of the American Physical Therapy Association · 2016
    Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Physical Fitness and the Level of Pain Intensity in Adolescents: A School-based Study.International journal of environmental research and public health · 2019
    Article
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Stacy Stolzman1Clinical and Translational Rehabilitation Health Sciences, Department of Physical Therapy, Marquette University, Milwaukee, WI; 2Program in Exercise Science, Department of Physical Therapy, Marquette University, Milwaukee, WI; and 3Herma Heart Center, Children's Hospital of Wisconsin, Milwaukee, WI.
Michael Danduran
Sandra K Hunter
Marie Hoeger Bement
Marquette University · US

Funding

Clincal and Translational Science AwardUL1TR000055 · NCATS · MEDICAL COLLEGE OF WISCONSIN · PI SHAKER, REZA NONE · 2012 to 2015
$11.3M
NCATS NIH HHS 8UL1TR000055NCATS NIH HHS UL1 TR000055
6 · The paper itself

Abstract

introductionPain reports are greater with increasing weight status, and exercise can reduce pain perception. It is unknown, however, whether exercise can relieve pain in adolescents of varying weight status. The purpose of this study was to determine whether adolescents across weight status report pain relief after high-intensity aerobic exercise (exercise-induced hypoalgesia (EIH)).

methodsSixty-two adolescents (15.1 ± 1.8 yr, 29 males) participated in the following three sessions: 1) pressure pain thresholds (PPT) before and after quiet rest, clinical pain (McGill Pain Questionnaire), and physical activity levels (self-report and ActiSleep Plus Monitors) were measured, 2) PPT were measured with a computerized algometer at the fourth finger's nailbed, middle deltoid muscle, and quadriceps muscle before and after maximal oxygen uptake test (V˙O2max Bruce Treadmill Protocol), and 3) body composition was measured with dual-energy x-ray absorptiometry.

resultsAll adolescents met criteria for V˙O2max. On the basis of body mass index z-score, adolescents were categorized as having normal weight (n = 33) or being overweight/obese (n = 29). PPT increased after exercise (EIH) and were unchanged with quiet rest (trial × session, P = 0.02). EIH was similar across the three sites and between normal-weight and overweight/obese adolescents. Physical activity and clinical pain were not correlated with EIH. Overweight/obese adolescents had similar absolute V˙O2max (L·min(-1)) but lower relative V˙O2max (mL·kg(-1)·min(-1)) compared with normal-weight adolescents. When adolescents were categorized using FitnessGram standards as unfit (n = 15) and fit (n = 46), the EIH response was similar between fitness levels.

conclusionsThis study is the first to establish that both overweight and normal-weight adolescents experience EIH. EIH after high-intensity aerobic exercise was robust in adolescents regardless of weight status and not influenced by physical fitness.

Indexed as

Body WeightAdolescentBody CompositionBody Mass IndexChildExerciseFemaleHumansMaleObesityOverweightOxygen ConsumptionPain ThresholdPhysical FitnessQuality of Life

Identifiers

PMID25856681
PMCPMC4598265
OpenAlexW2327482266

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.