Evidence map›Paper›PMID 25856487›Full record

ReviewNeuron2015

Towards large-scale, human-based, mesoscopic neurotechnologies.

Edward F Chang

Abstract readReview
In one paragraph

Review in Neuron, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 94 papers.

0numbers the graph read from it
0cells of the map it votes in
94citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

94 citing papers in PubMed.

  1. Trial
  2. The human hippocampus contributes to both the recollection and familiarity components of recognition memory.Proceedings of the National Academy of Sciences of the United States of America · 2015
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  19. Direct-Print 3D Electrodes for Large-Scale, High-Density, and Customizable Neural Interfaces.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
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  20. Article

34 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Edward F ChangDepartment of Neurological Surgery and Department of Physiology, University of California, San Francisco, 675 Nelson Rising Lane, Room 511, San Francisco, CA 94158, USA. Electronic address: edward.chang@ucsf.edu.

Funding

Functional organization of the superior temporal gyrus for speech perceptionR01DC012379 · NIDCD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Edward Chang · 2012 to 2026
$8.3M
Functional Architecture of Speech Motor CortexU01NS098971 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHANG, EDWARD · 2016 to 2018
$3.5M
NIDCD NIH HHS R01 DC012379NIDCD NIH HHS R01-DC012379NIH HHS DP2-OD00862NINDS NIH HHS U01 NS098971
6 · The paper itself

Abstract

Direct human brain recordings have transformed the scope of neuroscience in the past decade. Progress has relied upon currently available neurophysiological approaches in the context of patients undergoing neurosurgical procedures for medical treatment. While this setting has provided precious opportunities for scientific research, it also has presented significant constraints on the development of new neurotechnologies. A major challenge now is how to achieve high-resolution spatiotemporal neural recordings at a large scale. By narrowing the gap between current approaches, new directions tailored to the mesoscopic (intermediate) scale of resolution may overcome the barriers towards safe and reliable human-based neurotechnology development, with major implications for advancing both basic research and clinical translation.

Indexed as

Biomedical EngineeringDatasets as TopicNeurosciencesBrainHumans

Identifiers

PMID25856487
PMCPMC5810414

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.