ReviewNeuron2015
Neuromechanical principles underlying movement modularity and their implications for rehabilitation.
Review in Neuron, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 219 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Wearable for Post-stroke Rehabilitative Multi-muscle Stimulation Inspired by the Natural Organization of Neuromuscular Control
Examining the Effects of Operant Conditioning of Wrist Extensor MEP on Arm Intermuscular Coordination After Stroke
Neuromechanical Mechanisms of Exosuit-assisted Gait Rehabilitation After Stroke
Who cites it
219 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Walking speed is not the best outcome to evaluate the effect of robotic assisted gait training in people with motor incomplete Spinal Cord Injury: A Systematic Review with meta-analysis.The journal of spinal cord medicine · 2019Pooled it
- Synergy-based Functional Electrical Stimulation for gait rehabilitation in chronic stroke: a pilot study.Frontiers in rehabilitation sciences · 2026Trial
- Daily acute intermittent hypoxia combined with walking practice enhances walking performance but not intralimb motor coordination in persons with chronic incomplete spinal cord injury.Experimental neurology · 2021Trial
- A randomized controlled trial on the effects induced by robot-assisted and usual-care rehabilitation on upper limb muscle synergies in post-stroke subjects.Scientific reports · 2021Trial
- Changes in leg cycling muscle synergies after training augmented by functional electrical stimulation in subacute stroke survivors: a pilot study.Journal of neuroengineering and rehabilitation · 2020Trial
- Kinematic and Neuromuscular Adaptations in Incomplete Spinal Cord Injury after High- versus Low-Intensity Locomotor Training.Journal of neurotrauma · 2019Trial
- Neuromotor modules revealed by direct electrical stimulation of the human primary motor cortex.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Effects of Pre-Competition Neuromuscular Electrical Stimulation Activation on Forward Lunge Performance and Neuromuscular Control in Squash Athletes: An Analysis Based on Timing and Electromyographic Sensors.Sensors (Basel, Switzerland) · 2026Article
- Task-Dependent Reorganization of Ankle-Knee Mechanical Coordination Revealed by Moment-Moment Phase Space Analysis.Journal of functional morphology and kinesiology · 2026Article
- Pattern-Matched Powered Gait Orthosis Training in Patients with Neurological Gait Impairment: A Multicenter Prospective Pilot Study of Hip and Knee-Ankle-Foot Orthoses.Journal of clinical medicine · 2026Article
- A spinal substrate for modular control of natural behavior.bioRxiv : the preprint server for biology · 2026Article
- Reproducible Research: Computational Design of Personalized Clinical Treatments for Walking Impairments Using the Neuromusculoskeletal Modeling Pipeline.bioRxiv : the preprint server for biology · 2026Article
- Neuromuscular Adaptation to Varying Drop Jump Heights: A Muscle Synergy Approach in Elite Handball Players.Journal of human kinetics · 2026Article
- The Differential Effects of Fast Walking Speed on Muscle Coactivation in the Paretic and Non-Paretic Extremities Post-Stroke.Neurorehabilitation and neural repair · 2026Article
- Locomotion engages context-dependent motor strategies for head stabilization in primates.Communications biology · 2026Article
- Neuromechanical gait signatures reveal holistic biomechanical responses to walking speed modulation in stroke survivors.Scientific reports · 2026Article
- The role of independent walking in the maturation of the spinal locomotor output in children with cerebral palsy.Frontiers in physiology · 2026Article
- Muscle synergy characteristics during hands-and-knees crawling in children aged 4-6 years.PloS one · 2026Article
- Neuromechanical characteristics of breaststroke in adolescent swimmers across different performance levels: a comparative analysis.Frontiers in bioengineering and biotechnology · 2026Article
- Ground gradient affects stride-to-stride fluctuations and gait variability in overground walking.European journal of applied physiology · 2026Article
159 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Neuromechanical principles define the properties and problems that shape neural solutions for movement. Although the theoretical and experimental evidence is debated, we present arguments for consistent structures in motor patterns, i.e., motor modules, that are neuromechanical solutions for movement particular to an individual and shaped by evolutionary, developmental, and learning processes. As a consequence, motor modules may be useful in assessing sensorimotor deficits specific to an individual and define targets for the rational development of novel rehabilitation therapies that enhance neural plasticity and sculpt motor recovery. We propose that motor module organization is disrupted and may be improved by therapy in spinal cord injury, stroke, and Parkinson's disease. Recent studies provide insights into the yet-unknown underlying neural mechanisms of motor modules, motor impairment, and motor learning and may lead to better understanding of the causal nature of modularity and its underlying neural substrates.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.