Evidence map›Paper›PMID 25856477›Full record

ArticleNeuron2015

Gene regulation: it matters who you hang out with.

Tomohiro Masuda, Cynthia A Berlinicke, Donald J Zack

Open access · bronzeAbstract readComment
PubMed Publisher
In one paragraph

Article in Neuron, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 94% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Tomohiro MasudaWilmer Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.
Cynthia A BerlinickeWilmer Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.
Donald J ZackWilmer Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA. Electronic address: donzack@gmail.com.
Johns Hopkins University · US

Funding

REGULATION OF RHODOPSIN GENE EXPRESSIONR01EY009769 · NEI · JOHNS HOPKINS UNIVERSITY · PI ZACK, DONALD J. · 1992 to 2014
$8.1M
6 · The paper itself

Abstract

How broadly expressed transcription factors contribute to tissue-specific gene expression is not well understood. Andzelm, Cherry et al. (2015) demonstrate that myocyte enhancer factor 2D (MEF2D) binds and activates retina-specific regulatory regions by cooperative interaction with the tissue-specific transcription factor CRX.

Indexed as

AnimalsGene Expression Regulation, DevelopmentalHomeodomain ProteinsPhotoreceptor CellsRetinaTrans-ActivatorsHomeodomain ProteinsTrans-Activators

Identifiers

PMID25856477
OpenAlexW2151638738

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.