ArticlePLoS pathogens2015
Does the arthropod microbiota impact the establishment of vector-borne diseases in mammalian hosts?
Article in PLoS pathogens, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
29 citing papers in PubMed.
- Stage- and host-dependent microbiome remodeling and reciprocal changes betweenMicrobiology spectrum · 2026Article
- Differential impact of spotted fever groupFrontiers in microbiology · 2025Article
- Isolation and characterization of the midgut microbiota of Aedes albopictus to identify suitable candidates for paratransgenesis.European journal of public health · 2025Article
- Cross-alteration of murine skin and tick microbiome concomitant with pathogen transmission after Ixodes ricinus bite.Microbiome · 2023Article
- Frankenbacteriosis targeting interactions between pathogen and symbiont to control infection in the tick vector.iScience · 2023Article
- Bacterial Microbiota from Lab-Reared and Field-CapturedMicroorganisms · 2023Article
- Skin infectome of patients with a tick bite history.Frontiers in cellular and infection microbiology · 2023Article
- Aquaculture production of hatchling Hawaiian Bobtail Squid (Euprymna scolopes) is negatively impacted by decreasing environmental microbiome diversity.Journal of applied microbiology · 2022Article
- Diversity of midgut bacteria in larvae and females of Aedes aegypti and Aedes albopictus from Gampaha District, Sri Lanka.Parasites & vectors · 2021Article
- Data analysis workflow for the detection of canine vector-borne pathogens using 16 S rRNA Next-Generation Sequencing.BMC veterinary research · 2021Article
- Induced Transient Immune Tolerance in Ticks and Vertebrate Host: A Keystone of Tick-Borne Diseases?Frontiers in immunology · 2021Review
- The Diversity of Midgut Bacteria among Wild-CaughtBioMed research international · 2020Article
- Microbiome diversity in Diaphorina citri populations from Kenya and Tanzania shows links to China.PloS one · 2020Article
- Molecular Characterization of Culturable Aerobic Bacteria in the Midgut of Field-CaughtBioMed research international · 2020Article
- The Vector - Host - Pathogen Interface: The Next Frontier in the Battle Against Mosquito-Borne Viral Diseases?Frontiers in cellular and infection microbiology · 2020Review
- Naturally Occurring Microbiota Associated with Mosquito Breeding Habitats and Their Effects on Mosquito Larvae.BioMed research international · 2020Review
- Regional biogeography of microbiota composition in the Chagas disease vector Rhodnius pallescens.Parasites & vectors · 2019Article
- Microbiota variations inPeerJ · 2019Article
- Ixodes scapularis does not harbor a stable midgut microbiome.The ISME journal · 2018Article
- Chrysomya megacephala larvae feeding favourably influences manure microbiome, heavy metal stability and greenhouse gas emissions.Microbial biotechnology · 2018Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
The impact of the microbiota on the immune status of its host is a source of intense research and publicity. In comparison, the effect of arthropod microbiota on vector-borne infectious diseases has received little attention. A better understanding of the vector microbiota in relation to mammalian host immune responses is vital, as it can lead to strategies that affect transmission and improve vaccine design in a field of research where few vaccines exist and effective treatment is rare. Recent demonstrations of how microbiota decrease pathogen development in arthropods, and thus alter vector permissiveness to vector-borne diseases (VBDs), have led to renewed interest. However, hypotheses on the interactions between the arthropod-derived microbiota and the mammalian hosts have yet to be addressed. Advances in DNA sequencing technology, increased yield and falling costs, mean that these studies are now feasible for many microbiologists and entomologists. Here, we distill current knowledge and put forward key questions and experimental designs to shed light on this burgeoning research topic.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.