ArticlePhysics in medicine and biology2015
Design factors of intravascular dual frequency transducers for super-harmonic contrast imaging and acoustic angiography.
Article in Physics in medicine and biology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Functional Materials for ICE and IVUS Piezoelectric Transducers: A Review.Sensors (Basel, Switzerland) · 2026Review
- Biopsy Needle Integrated with Rotational Oblique Spectral Ultrasound (ROSUS) Imaging.Sensors (Basel, Switzerland) · 2026Article
- Millisecond-level transient heating and temperature monitoring technique for ultrasound-induced thermal strain imaging.Theranostics · 2025Article
- High-Frequency, 2-mm-Diameter Forward-Viewing 2-D Array for 3-D Intracoronary Blood Flow Imaging.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2024Article
- A Backing-Layer-Shared Miniature Dual-Frequency Ultrasound Probe for Intravascular Ultrasound Imaging: In Vitro and Ex Vivo Validations.Biosensors · 2023Article
- Novel ultrasound techniques in the identification of vulnerable plaques-an updated review of the literature.Frontiers in cardiovascular medicine · 2023Review
- Dual-Resonance (16/32 MHz) Piezoelectric Transducer With a Single Electrical Connection for Forward-Viewing Robotic Guidewire.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2022Article
- Mechanically Rotating Intravascular Ultrasound (IVUS) Transducer: A Review.Sensors (Basel, Switzerland) · 2021Review
- Recent Advances in Transducers for Intravascular Ultrasound (IVUS) Imaging.Sensors (Basel, Switzerland) · 2021Review
- High contrast power Doppler imaging in side-viewing intravascular ultrasound imaging via angular compounding.Ultrasonics · 2020Article
- All-Optical Rotational Ultrasound Imaging.Scientific reports · 2019Article
- Development of High-Frequency (>60 MHz) Intravascular Ultrasound (IVUS) Transducer by Using Asymmetric Electrodes for Improved Beam Profile.Sensors (Basel, Switzerland) · 2018Article
- Super-resolution ultrasound imaging method for microvasculature in vivo with a high temporal accuracy.Scientific reports · 2018Article
- A 35 MHz/105 MHz Dual-Element Focused Transducer for Intravascular Ultrasound Tissue Imaging Using the Third Harmonic.Sensors (Basel, Switzerland) · 2018Article
- Combining Subharmonic and Ultraharmonic Modes for Intravascular Ultrasound Imaging: A Preliminary Evaluation.Ultrasound in medicine & biology · 2017Article
- Intravascular Ultrasound Imaging With Virtual Source Synthetic Aperture Focusing and Coherence Factor Weighting.IEEE transactions on medical imaging · 2017Article
- Contrast Enhanced Superharmonic Imaging for Acoustic Angiography Using Reduced Form-Factor Lateral Mode Transmitters for Intravascular and Intracavity Applications.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2017Article
- Superharmonic Imaging for Medical Ultrasound: a Review.Journal of medical systems · 2016Review
- Ultrasonic Transducer-Guided Electrochemical Impedance Spectroscopy to Assess Lipid-Laden Plaques.Sensors and actuators. B, Chemical · 2016Article
- An Integrated System for Superharmonic Contrast-Enhanced Ultrasound Imaging: Design and Intravascular Phantom Imaging Study.IEEE transactions on bio-medical engineering · 2016Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Imaging of coronary vasa vasorum may lead to assessment of the vulnerable plaque development in diagnosis of atherosclerosis diseases. Dual frequency transducers capable of detection of microbubble super-harmonics have shown promise as a new contrast-enhanced intravascular ultrasound (CE-IVUS) platform with the capability of vasa vasorum imaging. Contrast-to-tissue ratio (CTR) in CE-IVUS imaging can be closely associated with low frequency transmitter performance. In this paper, transducer designs encompassing different transducer layouts, transmitting frequencies, and transducer materials are compared for optimization of imaging performance. In the layout selection, the stacked configuration showed superior super-harmonic imaging compared with the interleaved configuration. In the transmitter frequency selection, a decrease in frequency from 6.5 MHz to 5 MHz resulted in an increase of CTR from 15 dB to 22 dB when receiving frequency was kept constant at 30 MHz. In the material selection, the dual frequency transducer with the lead magnesium niobate-lead titanate (PMN-PT) 1-3 composite transmitter yielded higher axial resolution compared to single crystal transmitters (70 μm compared to 150 μm pulse length). These comparisons provide guidelines for the design of intravascular acoustic angiography transducers.
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Registered trials
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