Evidence map›Paper›PMID 25855782›Full record

ArticleJournal of the American Society of Nephrology : JASN2015

Outcomes of Elderly Patients after Predialysis Vascular Access Creation.

Timmy Lee, Mae Thamer, Yi Zhang, Qian Zhang, Michael Allon

Registry-linked trialAbstract read
In one paragraph

Article in Journal of the American Society of Nephrology : JASN, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05654103 (Randomized Controlled Trial Comparing endoAVF Versus surgAVF), which is not on this map. Cited by 46 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05654103 naactive not recruitingnot on this mapstarted 2024, after this paper: background citation

Randomized Controlled Trial Comparing endoAVF Versus surgAVF

TypeinterventionalSponsorUniversity of California, Los AngelesRan2024 to 2027Enrolled90ConditionsEnd Stage Renal Disease on DialysisArmsendoAVF, surgAVF
3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Trial
  3. Observational
  4. Article
  5. Article
  6. Preemptive Vascular Access Placement and Mortality Risk in Hemodialysis Patients: A Real-World Single-Center Study.Hemodialysis international. International Symposium on Home Hemodialysis · 2026
    Article
  7. Optimizing Dialysis Vascular Access: Moving beyond Fistula First.Clinical journal of the American Society of Nephrology : CJASN · 2026
    Review
  8. Article
  9. Review
  10. Article
  11. Quality Metrics in Dialysis: A Welcome Change for Vascular Access.Advances in kidney disease and health · 2025
    Review
  12. Article
  13. Observational
  14. Article
  15. Clinical impact of the Kidney Failure Risk Equation for vascular access planning.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2024
    Article
  16. Article
  17. Article
  18. Review
  19. Shared decision making in elderly patients with kidney failure.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2024
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Timmy LeeDivision of Nephrology, Department of Medicine, University of Alabama, Birmingham, Alabama; Veterans Affairs Medical Center, Birmingham, Alabama; and.
Mae ThamerMedical Technology and Practice Patterns Institute, Bethesda, Maryland.
Yi ZhangMedical Technology and Practice Patterns Institute, Bethesda, Maryland.
Qian ZhangMedical Technology and Practice Patterns Institute, Bethesda, Maryland.
Michael AllonDivision of Nephrology, Department of Medicine, University of Alabama, Birmingham, Alabama; mdallon@uab.edu.

Funding

Vascular abnormalities in patients receiving a dialysis access.R01DK085027 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ALLON, MICHAEL · 2010 to 2013
$1.5M
Choice of vascular access and patient outcomes among older hemodialysis patientsR21DK104248 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ALLON, MICHAEL · 2015 to 2016
$432k
Creation of a Risk-scoring Algorithm for Early Mortality Among Elderly ESRD PatieR21AG043516 · NIA · MEDICAL TECHNOLOGY AND PRACTICE PATTERNS · PI THAMER, MAE · 2013 to 2014
$340k
NIA NIH HHS R21 AG043516NIA NIH HHS R21-AG043516NIDDK NIH HHS R01 DK085027NIDDK NIH HHS R01-DK085027NIDDK NIH HHS R21 DK104248
6 · The paper itself

Abstract

Uniform vascular access guidelines for elderly patients may be inappropriate because of the competing risk of death, high rate of arteriovenous fistula (AVF) maturation failure, and poor vascular access outcomes in this population. However, the outcomes in elderly patients with advanced CKD who receive permanent vascular access before dialysis initiation are unclear. We identified a large nationally representative cohort of 3418 elderly patients (aged ≥ 70 years) with CKD undergoing predialysis AVF or arteriovenous graft (AVG) creation from 2004 to 2009, and assessed the frequencies of dialysis initiation, death before dialysis initiation, and dialysis-free survival for 2 years after vascular access creation. In all, 67% of patients with predialysis AVF and 71% of patients with predialysis AVG creation initiated dialysis within 2 years of access placement, but the overall risk of dialysis initiation was modified by patient age and race. Only one half of patients initiated dialysis with a functioning AVF or AVG; 46.8% of AVFs were created <90 days before dialysis initiation. Catheter dependence at dialysis initiation was more common in patients receiving predialysis AVF than in patients receiving AVG (46.0% versus 28.5%; P<0.001). In conclusion, most elderly patients with advanced CKD who received predialysis vascular access creation initiated dialysis within 2 years. As a consequence of late predialysis placement or maturation failure, almost one half of patients receiving AVFs initiated dialysis with a catheter. Insertion of an AVG closer to dialysis initiation may serve as a "catheter-sparing" approach and allow delay of permanent access placement in selected elderly patients with CKD.

Indexed as

AgedAged, 80 and overAge FactorsArteriovenous Shunt, SurgicalBlack or African AmericanCathetersComorbidityFemaleHumansKidney Failure, ChronicMaleRenal DialysisSurvival RateTime FactorsTreatment OutcomeUnited Statesarteriovenous fistulaarteriovenous graftvascular access

Identifiers

PMID25855782
PMCPMC4657836

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.