ArticleJournal of the American Geriatrics Society2015
Effect of hospitalization on inappropriate prescribing in elderly Medicare beneficiaries.
Article in Journal of the American Geriatrics Society, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 19 citations in OpenAlex.
- A systematic review of methods for determining cross-sectional active medications using pharmacy databases.Pharmacoepidemiology and drug safety · 2019Pooled it
- Determinants of Potentially Inappropriate Medication Use in Long-Term and Acute Care Settings: A Systematic Review.Journal of the American Medical Directors Association · 2017Pooled it
- Potentially inappropriate medications in older adults with Parkinson disease before and after hospitalization for injury.Parkinsonism & related disorders · 2023Article
- Older Patient and Surrogate Attitudes Toward Deprescribing During the Transition From Acute to Post-Acute Care.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2022Article
- Impact of emergency hospital admissions on patterns of primary care prescribing: a retrospective cohort analysis of electronic records in England.The British journal of general practice : the journal of the Royal College of General Practitioners · 2020Article
- Potentially Inappropriate Medication Prescribing and Risk of Unplanned Hospitalization among the Elderly: A Self-Matched, Case-Crossover Study.Drug safety · 2018Article
- Article
- Health Service Use, Costs, and Adverse Events Associated with Potentially Inappropriate Medication in Old Age in Germany: Retrospective Matched Cohort Study.Drugs & aging · 2017Article
- Medications associated with geriatric syndromes and their prevalence in older hospitalized adults discharged to skilled nursing facilities.Journal of hospital medicine · 2016Article
- Associations between Anticholinergic Burden and Adverse Health Outcomes in Parkinson Disease.PloS one · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
objectivesTo determine whether acute hospitalization is associated with a change in potentially inappropriate medication (PIM) use and whether use varies across geographic region.
designObservational.
settingContinental United States.
participantsMedicare beneficiaries aged 65 and older hospitalized for acute myocardial infarction (AMI) during 2007-08. MEASUREMENTS: Potentially inappropriate medication use was defined according to the High-Risk Medications in Elderly Adults quality indicator from the Healthcare Effectiveness Data and Information Set. Prevalence of outpatient PIM use was determined at admission and discharge and then used to identify medications discontinued during hospitalization and incident medications started during this period.
resultsOf 124,051 older adults hospitalized for AMI, 9,607 (7.7%) were outpatient PIM users at admission, which increased to 8.6% at discharge (P < .001). Admission PIM rates varied according to geographic region, as did the effect of hospitalization. Admission PIM use was lowest in the northeast and remained unchanged during hospitalization (5.1-5.1%, P = .95). In contrast, admission PIM use was highest in the south and increased significantly during hospitalization (9.9-11.4%, P < .001). PIM use also increased from the long-term perspective, with 6-month period prevalence rates of 22.6% before admission and 24.6% after discharge (P < .001).
conclusionDespite intervention studies demonstrating up to 80% reduction in PIM use during acute hospitalization, a significant increase in PIM use was observed in a naturalistic setting in Medicare beneficiaries with AMI. Further research is needed to develop an approach to minimizing PIM use in the inpatient setting that is cost-effective and suitable for widespread implementation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.