Evidence map›Paper›PMID 25854971›Full record

ArticleBMJ open2015

Hydrogen sulfide and traffic-related air pollutants in association with increased mortality: a case-crossover study in Reykjavik, Iceland.

Ragnhildur Gudrun Finnbjornsdottir, Anna Oudin, Bjarki Thor Elvarsson, Thorarinn Gislason, Vilhjalmur Rafnsson

Abstract read
In one paragraph

Article in BMJ open, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. The Scientific Basis for Occupational Exposure Limits for Hydrogen Sulphide-A Critical Commentary.International journal of environmental research and public health · 2021
    Pooled it
  2. Article
  3. Cold Climate Impact on Air-Pollution-Related Health Outcomes: A Scoping Review.International journal of environmental research and public health · 2022
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ragnhildur Gudrun FinnbjornsdottirCentre of Public Health Sciences, University of Iceland, Reykjavik, Iceland.
Anna OudinOccupational and Environmental Medicine, Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.ORCID http://orcid.org/0000-0002-9876-0627
Bjarki Thor ElvarssonScience Institute, University of Iceland, Reykjavik, Iceland.
Thorarinn GislasonFaculty of Medicine, University of Iceland, Reykjavik, Iceland Department of Allergy and Respiratory Medicine and Sleep, Landspitali University Hospital, Reykjavik, Iceland.
Vilhjalmur RafnssonDepartment of Preventive Medicine, University of Iceland, Reykjavik, Iceland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo study the association between daily mortality and short-term increases in air pollutants, both traffic-related and the geothermal source-specific hydrogen sulfide (H₂S).

designPopulation-based, time stratified case-crossover. A lag time to 4 days was considered. Seasonal, gender and age stratification were calculated. Also, the best-fit lag when introducing H₂S >7 µg/m(3) was selected by the Akaike Information Criterion (AIC).

settingThe population of the greater Reykjavik area (n=181,558) during 2003-2009.

participantsCases were defined as individuals living in the Reykjavik capital area, 18 years or older (N=138,657), who died due to all natural causes (ICD-10 codes A00-R99) other than injury, poisoning and certain other consequences of external causes, or cardiovascular disease (ICD-10 codes I00-I99) during the study period.

main outcome measurePercentage increases in risk of death (IR%) following an interquartile range increase in pollutants.

resultsThe total number of deaths due to all natural causes was 7679 and due to cardiovascular diseases was 3033. The interquartile range increased concentrations of H₂S (2.6 µg/m(3)) were associated with daily all natural cause mortality in the Reykjavik capital area. The IR% was statistically significant during the summer season (lag 1: IR%=5.05, 95% CI 0.61 to 9.68; lag 2: IR%=5.09, 95% CI 0.44 to 9.97), among males (lag 0: IR%=2.26, 95% CI 0.23 to 4.44), and among the elderly (lag 0: IR%=1.94, 95% CI 0.12 to 1.04; lag 1: IR%=1.99, 95% CI 0.21 to 1.04), when adjusted for traffic-related pollutants and meteorological variables. The traffic-related pollutants were generally not associated with statistical significant IR%s.

conclusionsThe results suggest that ambient H₂S air pollution may increase mortality in Reykjavik, Iceland. To the best of our knowledge, ambient H₂S exposure has not previously been associated with increased mortality in population-based studies and therefore the results should be interpreted with caution. Further studies are warranted to confirm or refute whether H₂S exposure induces premature deaths.

Indexed as

Air PollutantsAir PollutionCross-Over StudiesEnvironmental ExposureHumansHydrogen SulfideIcelandMotor VehiclesParticulate MatterPopulation SurveillanceRespiratory Tract DiseasesRisk AssessmentAir PollutantsHydrogen SulfideParticulate MatterAir pollutionCross-over studiesGeothermalHydrogen SulfidePower PlantsRegistries

Identifiers

PMID25854971
PMCPMC4390682

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.