SynthesisNutrients2015
Enteral nutrition in dementia: a systematic review.
Synthesis in Nutrients, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 60 citations in OpenAlex.
- Enteral tube feeding for people with severe dementia.The Cochrane database of systematic reviews · 2021Pooled it
- Mapping and understanding the decision-making process for providing nutrition and hydration to people living with dementia: a systematic review.BMC geriatrics · 2020Pooled it
- Review
- Use of Feeding Tubes Among Hospitalized Older Adults With Dementia.JAMA network open · 2025Article
- Mapping an evidence-based end-of-life care framework for older adults in Chinese nursing homes: protocol for a scoping review.BMJ open · 2024Article
- Nutrition and Outcome of 100 Endoscopic Gastrostomy-Fed Citizens with Severe Dementia.Nutrients · 2023Article
- Outcomes and Predictors of In-Hospital Mortality among Older Patients with Dementia.Journal of clinical medicine · 2022Article
- Current Evidence on the Association of Micronutrient Malnutrition with Mild Cognitive Impairment, Frailty, and Cognitive Frailty among Older Adults: A Scoping Review.International journal of environmental research and public health · 2022Article
- Comorbidity patterns in institutionalized older adults affected by dementia.Alzheimer's & dementia (Amsterdam, Netherlands) · 2022Article
- Machine Learning-Based Assessment of Cognitive Impairment Using Time-Resolved Near-Infrared Spectroscopy and Basic Blood Test.Frontiers in neurology · 2021Article
- Percutaneous endoscopic gastrostomy - Too often? Too late? Who are the right patients for gastrostomy?World journal of gastroenterology · 2020Review
- Deep Learning-Based Screening Test for Cognitive Impairment Using Basic Blood Test Data for Health Examination.Frontiers in neurology · 2020Article
- Association between delivery methods for enteral nutrition and physical status among older adults.BMC nutrition · 2020Article
- Cachexia and advanced dementia.Journal of cachexia, sarcopenia and muscle · 2019Review
- Percutaneous Endoscopic Gastrostomy Tube Removal for Patients With Advanced Dementia: Case Series Study.Annals of geriatric medicine and research · 2019Article
- Tube Feeding in Individuals with Advanced Dementia: A Review of Its Burdens and Perceived Benefits.Journal of aging research · 2019Review
- Ethical Issues in the Treatment of Late-Stage Alzheimer's Disease.Journal of Alzheimer's disease : JAD · 2019Review
- Nutritional Status and Nutritional Treatment Are Related to Outcomes and Mortality in Older Adults with Hip Fracture.Nutrients · 2018Review
- Tube feeding decreases pneumonia rate in patients with severe dementia: comparison between pre- and post-intervention.BMC geriatrics · 2017Article
- Recent Advances in Enteral Nutrition.Nutrients · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this systematic review is to evaluate the role of enteral nutrition in dementia. The prevalence of dementia is predicted to rise worldwide partly due to an aging population. People with dementia may experience both cognitive and physical complications that impact on their nutritional intake. Malnutrition and weight loss in dementia correlates with cognitive decline and the progress of the disease. An intervention for long term eating difficulties is the provision of enteral nutrition through a Percutaneous Endoscopic Gastrostomy tube to improve both nutritional parameters and quality of life. Enteral nutrition in dementia has traditionally been discouraged, although further understanding of physical, nutritional and quality of life outcomes are required. The following electronic databases were searched: EBSCO Host, MEDLINE, PubMed, Cochrane Database of Systematic Reviews and Google Scholar for publications from 1st January 2008 and up to and including 1st January 2014. Inclusion criteria included the following outcomes: mortality, aspiration pneumonia, pressure sores, nutritional parameters and quality of life. Each study included separate analysis for patients with a diagnosis of dementia and/or neurological disease. Retrospective and prospective observational studies were included. No differences in mortality were found for patients with dementia, without dementia or other neurological disorders. Risk factors for poor survival included decreased or decreasing serum albumin levels, increasing age or over 80 years and male gender. Evidence regarding pneumonia was limited, although did not impact on mortality. No studies explored pressure sores or quality of life.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.