ArticleJournal of artificial organs : the official journal of the Japanese Society for Artificial Organs2015
Establishment of a total liquid ventilation system using saline-based oxygen micro/nano-bubble dispersions in rats.
Article in Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed, 8 citations in OpenAlex.
- Development of quantitative and concise measurement method of oxygen in fine bubble dispersion.PloS one · 2022Article
- Total alveolar lavage with oxygen fine bubble dispersion directly improves lipopolysaccharide-induced acute respiratory distress syndrome of rats.Scientific reports · 2020Article
- Efficient COJournal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2018Article
- Topical oxygen therapy & micro/nanobubbles: a new modality for tissue oxygen delivery.International wound journal · 2018Review
- Journal of Artificial Organs 2015: the year in review : Journal of Artificial Organs Editorial Committee.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2016Review
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Micro/nano-bubbles are practical nanomaterials designed to increase the gas content in liquids. We attempted to use oxygen micro/nano-bubble dispersions as an oxygen-rich liquid as a means for total liquid ventilation. To determine the oxygen content in the bubble dispersion, a new method based on a spectrophotometric change between oxy- and deoxy-hemoglobin was established. The oxygen micro/nano-bubble dispersion was supplied to an experimental total ventilation liquid in anesthetic rats. Though the amount of dissolving oxygen was as low as 6 mg/L in physiological saline, the oxygen content in the oxygen micro/nano-bubble dispersion was increased to 45 mg/L. The positive correlation between the oxygen content and the life-saving time under liquid ventilation clearly indicates that the life-saving time is prolonged by increasing the oxygen content in the oxygen micro/nano-bubble dispersion. This is the first report indicating that the oxygen micro/nano-bubbles containing a sufficient amount of oxygen are useful in producing oxygen-rich liquid for the process of liquid ventilation.
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Registered trials
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