Evidence map›Paper›PMID 25854499›Full record

Trial reportKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2017

Early full weight-bearing versus 6-week partial weight-bearing after open wedge high tibial osteotomy leads to earlier improvement of the clinical results: a prospective, randomised evaluation.

S Schröter, A Ateschrang, W Löwe, H Nakayama, U Stöckle, C Ihle

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
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  5. Anatomical implant region - a critical determinant for the osteogenic potency of small extracellular vesicles and rhBMP-2.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025
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  14. Review
  15. [Osteotomies around the knee-part 1].Operative Orthopadie und Traumatologie · 2024
    Article
  16. Article
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  18. [Osteotomy close to the knee joint in adults].Orthopadie (Heidelberg, Germany) · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

S SchröterDepartment of Traumatology and Reconstructive Surgery, BG Traumacenter Tübingen, University of Tübingen, Schnarrenbergstr. 95, 72076, Tuebingen, Germany. schroeter.steffen@t-online.de.
A AteschrangDepartment of Traumatology and Reconstructive Surgery, BG Traumacenter Tübingen, University of Tübingen, Schnarrenbergstr. 95, 72076, Tuebingen, Germany.
W LöweDepartment of Traumatology and Reconstructive Surgery, BG Traumacenter Tübingen, University of Tübingen, Schnarrenbergstr. 95, 72076, Tuebingen, Germany.
H NakayamaHyogo College of Medicine, Osaka, Japan.
U StöckleDepartment of Traumatology and Reconstructive Surgery, BG Traumacenter Tübingen, University of Tübingen, Schnarrenbergstr. 95, 72076, Tuebingen, Germany.
C IhleDepartment of Traumatology and Reconstructive Surgery, BG Traumacenter Tübingen, University of Tübingen, Schnarrenbergstr. 95, 72076, Tuebingen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeOpen wedge high tibial osteotomy is a widespread treatment option in patients with varus malalignment and medial compartment osteoarthritis. There is no standardised protocol for post-operative rehabilitation available. The purpose of this study was to compare two post-operative rehabilitation protocols and to evaluate the clinical outcome of early full weight-bearing after open wedge HTO.

methodsOne hundred and twenty consecutive patients with varus malalignment and medial compartment osteoarthritis received an open wedge HTO using an angular locking plate fixation between December 2008 and December 2011. All patients were assigned randomly into one of two groups with different post-operative rehabilitation protocols (11-day vs. 6-week 20-kg partial weight-bearing). Clinical outcome was evaluated using established instruments (Lequesne, Lysholm, HSS and IKDC scores) preoperatively, 6, 12 and 18 months post-operatively. Deformity analysis was performed preoperatively and during follow-up.

resultsAll clinical scores showed a significant pre- to post-operative improvement. After 6 months, there was a higher improvement in the group of early full weight-bearing. The difference between preoperative and 6-month follow-up for the group with early full weight-bearing and for the group with 20-kg PWB for 6 weeks was 28 ± 26 and 18 ± 22, respectively, for the Lysholm score and -5.0 ± 5.1 and -3.0 ± 3.6, respectively, for the Lequesne score.

conclusionsEarly full weight-bearing (11-day 20-kg partial weight-bearing) after open wedge HTO without bone graft leads to earlier improvement of the clinical results and can be recommended for post-operative rehabilitation after open wedge HTO and fixation with an angular locking plate. LEVEL OF EVIDENCE: Therapeutic study, Level I.

Indexed as

Bone PlatesWeight-BearingAdultAftercareFemaleGenu VarumHumansKnee JointMaleMiddle AgedOsteoarthritis, KneeOsteotomyProspective StudiesTibiaTreatment OutcomeAftercareHTOOpen wedge high tibial osteotomyRehabilitationVarus deformityWeight-bearing

Identifiers

PMID25854499

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.