ArticleJournal of the American Geriatrics Society2015
Asthma control and cognitive function in a cohort of elderly adults.
Article in Journal of the American Geriatrics Society, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 32 citations in OpenAlex.
- Cognitive Impairment in Asthma: Emerging Evidence, Clinical Consequences, and Future Directions.Journal of clinical medicine · 2026Review
- Inferring multi-organ genetic connections using imaging and clinical data through Mendelian randomization.Nature biomedical engineering · 2026Article
- Asthma and cognitive dysfunction in older adults: the mediating role of systemic immune-inflammation index.Scientific reports · 2024Article
- Considering different Montreal Cognitive Assessment cutoff scores for older adults with asthma.Allergy and asthma proceedings · 2024Article
- Systemic Inflammation in Asthma: What Are the Risks and Impacts Outside the Airway?The journal of allergy and clinical immunology. In practice · 2024Review
- Exploring the link between the pediatric exposome, respiratory health, and executive function in children: a narrative review.Frontiers in public health · 2024Review
- The Association of Asthma with Anxiety, Depression, and Mild Cognitive Impairment among Middle-Aged and Elderly Individuals in Saudi Arabia.Behavioral sciences (Basel, Switzerland) · 2023Article
- Brain response in asthma: the role of "lung-brain" axis mediated by neuroimmune crosstalk.Frontiers in immunology · 2023Review
- Cerebral regional and network characteristics in asthma patients: a resting-state fMRI study.Frontiers of medicine · 2020Article
- Questionnaire Survey for Bronchial Asthma in Elderly Care Facilities.The Kobe journal of medical sciences · 2019Article
- Altered Regional Cerebral Blood Flow of Right Cerebellum Posterior Lobe in Asthmatic Patients With or Without Depressive Symptoms.Frontiers in psychiatry · 2018Article
- Recognition, diagnosis, and treatment of cognitive and psychiatric disorders in patients with COPD.International journal of chronic obstructive pulmonary disease · 2017Review
- Sleep quality disturbances and cognitive functioning in elderly patients with COPD.ERJ open research · 2016Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
objectivesTo determine whether poor asthma control is associated with cognitive impairment in a cohort of older, inner-city adults with asthma.
designProspective observational cohort study.
settingOutpatient practices in New York City and Chicago.
participantsIndividuals aged 60 and older with a physician diagnosis of asthma and without chronic obstructive pulmonary disease or a smoking history of 10 pack-years or more (N = 452). MEASUREMENTS: Cognitive assessments that included processing speed (pattern comparison, Trail-Making Test Part A), executive function (Trail-Making Test Part B), attention and working memory (letter number sequencing), immediate and delayed recall (Wechsler Memory Scale Story A), word fluency (animal naming), and global cognitive function (Mini-Mental State Examination) were administered. Asthma control was measured using the Asthma Control Questionnaire (ACQ) and airway obstruction using spirometry as the predicted forced expiratory volume at 1 second (FEV1) of less than 70%. Cognitive measures were modeled in linear and logistic regression models controlling for age, race, education, English proficiency, and income.
resultsParticipants had a mean age of 68; 41% had poor asthma control according to the ACQ, and 35% had FEV1 of less than 70%. Poor asthma control and FEV1 less than 70% were significantly associated with all measures of cognitive function in univariate analyses, although these associations lost their statistical significance after adjusting for age, education, English proficiency, and other covariates. The same pattern was observed when the outcomes were below-normal performance on the cognitive measures based on normative data.
conclusionPoor asthma control and airway obstruction are not associated with poor performance on various measures of cognitive function in older adults with asthma.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.