Evidence map›Paper›PMID 25853317›Full record

ArticleMolecules (Basel, Switzerland)2015

Organic-inorganic hybrid nanoparticles for bacterial inhibition: synthesis and characterization of doped and undoped ONPs with Ag/Au NPs.

Carlos Alberto Huerta Aguilar, Adriana Berenice Pérez Jiménez, Antonio Romero Silva, Navneet Kaur, Pandiyan Thangarasu, Jorge Manuel Vázquez Ramos, Narinder Singh

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Carlos Alberto Huerta AguilarFacultad de Química, Universidad Nacional Autónoma de México (UNAM), Ciudad Universitaria, Coyoacán, 04510 México D.F., Mexico. waitthinkandfast@hotmail.com.
Adriana Berenice Pérez JiménezFacultad de Química, Universidad Nacional Autónoma de México (UNAM), Ciudad Universitaria, Coyoacán, 04510 México D.F., Mexico. remin_1711@hotmail.com.
Antonio Romero SilvaFacultad de Química, Universidad Nacional Autónoma de México (UNAM), Ciudad Universitaria, Coyoacán, 04510 México D.F., Mexico. antromsil@comunidad.unam.mx.
Navneet KaurCentre for Nanoscience & Nanotechnology, Panjab University, Chandigarh, Panjab 160014, India. navneetkau@pu.ac.in.
Pandiyan ThangarasuFacultad de Química, Universidad Nacional Autónoma de México (UNAM), Ciudad Universitaria, Coyoacán, 04510 México D.F., Mexico. pandiyan@unam.mx.
Jorge Manuel Vázquez RamosFacultad de Química, Universidad Nacional Autónoma de México (UNAM), Ciudad Universitaria, Coyoacán, 04510 México D.F., Mexico.
Narinder SinghDepartment of Chemistry, Indian Institute of Technology Ropar, Rupnagar, Panjab 140001, India. narindarchem@gmail.com.

Funding

Cincinnati Center for Clinical and Translational Sciences and TrainingUL1TR000077 · NCATS · UNIVERSITY OF CINCINNATI · PI HEUBI, JAMES E., TSEVAT, JOEL · 2012 to 2014
$9.9M
NCATS NIH HHS UL1 TR000077
6 · The paper itself

Abstract

Organic nanoparticles (ONPs) of lipoic acid and its doped derivatives ONPs/Ag and ONPs/Au were prepared and characterized by UV-Visible, EDS, and TEM analysis. The antibacterial properties of the ONPs ONPs/Ag and ONPs/Au were tested against bacterial strains (Staphylococcus aureus, Bacillus cereus, Escherichia coli and Salmonella typhi). Minimal Inhibitory Concentration (MIC) and bacterial growth inhibition tests show that ONPs/Ag are more effective in limiting bacterial growth than other NPs, particularly, for Gram positive than for Gram-negative ones. The order of bacterial cell growth inhibition was ONPs/Ag > ONPs > ONPs/Au. The morphology of the cell membrane for the treated bacteria was analyzed by SEM. The nature of bond formation of LA with Ag or Au was analyzed by molecular orbital and density of state (DOS) using DFT.

Indexed as

GoldSilverAnti-Bacterial AgentsBacteriaMetal NanoparticlesMicrobial Sensitivity TestsMolecular StructureThioctic AcidAnti-Bacterial AgentsGoldSilverThioctic Acid

Identifiers

PMID25853317
PMCPMC6272726

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.