ArticleChemistry (Weinheim an der Bergstrasse, Germany)2015
Easy To Synthesize, Robust Organo-osmium Asymmetric Transfer Hydrogenation Catalysts.
Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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11 citing papers in PubMed.
- A ratiometric substrate for rapid evaluation of transfer hydrogenation efficiency in solution.Dalton transactions (Cambridge, England : 2003) · 2024Article
- Targeting cancer lactate metabolism with synergistic combinations of synthetic catalysts and monocarboxylate transporter inhibitors.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2023Article
- Rational Design of a Facially Coordinating P,N,N Ligand for Manganese-Catalysed Enantioselective Hydrogenation of Cyclic Ketones.Angewandte Chemie (International ed. in English) · 2023Article
- NMR studies of group 8 metallodrugs:Dalton transactions (Cambridge, England : 2003) · 2021Article
- Tracking Reactions of Asymmetric Organo-Osmium Transfer Hydrogenation Catalysts in Cancer Cells.Angewandte Chemie (International ed. in English) · 2021Article
- Transfer hydrogenation catalysis in cells.RSC chemical biology · 2021Review
- Artificial imine reductases: developments and future directions.RSC chemical biology · 2020Review
- Computational Prediction of Chiral Iron Complexes for Asymmetric Transfer Hydrogenation of Pyruvic Acid to Lactic Acid.Molecules (Basel, Switzerland) · 2020Article
- Asymmetric transfer hydrogenation by synthetic catalysts in cancer cells.Nature chemistry · 2018Article
- Half-Sandwich Ru(II) and Os(II) Bathophenanthroline Complexes Containing a Releasable Dichloroacetato Ligand.Molecules (Basel, Switzerland) · 2018Article
- Halide Control ofOrganometallics · 2017Article
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6 authors.
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Abstract
Asymmetric transfer hydrogenation (ATH) is an important process in organic synthesis for which the Noyori-type Ru(II) catalysts [(arene)Ru(Tsdiamine)] are now well established and widely used. We now demonstrate for the first time the catalytic activity of the osmium analogues. X-ray crystal structures of the 16-electron Os(II) catalysts are almost identical to those of Ru(II). Intriguingly the precursor complex was isolated as a dichlorido complex with a monodentate amine ligand. The Os(II) catalysts are readily synthesised (within 1 h) and exhibit excellent enantioselectivity in ATH reactions of ketones.
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