Evidence map›Paper›PMID 25852948›Full record

ArticleOpen heart

The no-touch vein graft for coronary artery bypass surgery preserves the left ventricular ejection fraction at 16 years postoperatively: long-term data from a longitudinal randomised trial.

Benny Johansson, Ninos Samano, Domingos Souza, Lennart Bodin, Derek Filbey, John D Mannion, Leif Bojö

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Open heart. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01686100 (CT-angiographic Follow Upp of Patients That Underwent Coronary Bypass Surgery Between 1993-1997. A Randomized Longitudinal Trial.), which is not on this map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01686100 nacompletednot on this map

CT-angiographic Follow Upp of Patients That Underwent Coronary Bypass Surgery Between 1993-1997. A Randomized Longitudinal Trial.

TypeinterventionalSponsorÖrebro County CouncilRan2010 to 2011Enrolled52ConditionsCoronary Artery DiseaseArmsNo touch technique, Conventional technique
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Pathological Conversion of Mouse Perivascular Adipose Tissue by Notch Activation.Arteriosclerosis, thrombosis, and vascular biology · 2020
    Article
  3. Review
  4. Saphenous vein: advances.Indian journal of thoracic and cardiovascular surgery · 2018
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Benny JohanssonDepartment of Clinical Physiology, Faculty of Medicine and Health , Örebro University , Örebro , Sweden.
Ninos SamanoDepartment of Cardiothoracic and Vascular Surgery, Faculty of Medicine and Health , Örebro University , Örebro , Sweden.
Domingos SouzaDepartment of Cardiothoracic and Vascular Surgery, Faculty of Medicine and Health , Örebro University , Örebro , Sweden.
Lennart BodinKarolinska Institute, Institute of Environmental Medicine, Unit of Intervention and Implementation Research , Stockholm , Sweden.
Derek FilbeyDepartment of Cardiothoracic and Vascular Surgery, Faculty of Medicine and Health , Örebro University , Örebro , Sweden.
John D MannionDepartment of Surgery , Bayhealth Medical Center , Dover, Delaware , USA.
Leif BojöDepartment of Clinical Physiology , Central Hospital , Karlstad , Sweden.
Örebro University · SEBayhealth Foundation · USKarlstad Central Hospital · SEKarolinska Institutet · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo assess the left ventricular heart function and the clinical outcome 16 years after coronary artery bypass surgery.

designIn a randomised trial, the no-touch (NT) vein graft in coronary artery bypass surgery has shown a superior patency rate, a slower progression of atherosclerosis and better clinical outcome compared to the conventional (C) vein graft at 8.5 years. All patients at mean time 16 years were offered an echocardiographic and clinical examination.

resultsIn the NT-group 34 patients and in the C-group 31 patients underwent an echocardiography examination. A significantly better left ventricle ejection fraction was seen in the NT-group compared to the C-group (57.9% vs 49.4%; p=0.011). The size of the left atrium in NT was 21.7 cm(2) compared to 23.9 cm(2) in C; p=0.034. No patient in NT had atrial fibrillation compared to five patients in C (p=0.021). Patients with a brain natriuretic peptide value (BNP) ≥150 was 30% in NT compared to 38% in C. Total mortality was 25% in NT vs 27% in C. Cardiac-related deaths were 8% and 12% in NT and C respectively.

conclusionsThe NT vein graft preserves the left ventricular ejection fraction after 16 years. A smaller left atrium, a lower BNP and no atrial fibrillation indicates an improved diastolic left ventricular function in the NT-group.

trial registrationThe study is registered with clinicaltrials.gov (NCT01686100) and The Research and Development registry in Sweden (no. 102841).

Indexed as

Vein graft Disease

Identifiers

PMID25852948
PMCPMC4379882
OpenAlexW2154742781

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.