Evidence map›Paper›PMID 25852305›Full record

ArticleNanoscale research letters2015

Targeted images of KB cells using folate-conjugated gold nanoparticles.

Pierson Rathinaraj, Kyubae Lee, Soo-Young Park, Inn-Kyu Kang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nanoscale research letters, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Pierson RathinarajSchool of Applied Chemical Engineering, Graduate School, Kyungpook National University, 80, Daehak-ro, Buk-gu, Daegu 702-701 South Korea.
Kyubae LeeSchool of Applied Chemical Engineering, Graduate School, Kyungpook National University, 80, Daehak-ro, Buk-gu, Daegu 702-701 South Korea.
Soo-Young ParkSchool of Applied Chemical Engineering, Graduate School, Kyungpook National University, 80, Daehak-ro, Buk-gu, Daegu 702-701 South Korea.
Inn-Kyu KangSchool of Applied Chemical Engineering, Graduate School, Kyungpook National University, 80, Daehak-ro, Buk-gu, Daegu 702-701 South Korea.
Kyungpook National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mercaptosuccinic acid-coated gold (GM) nanoparticles were prepared and characterized by transmission electron microscopy and dynamic light scattering. Folic acid (F) was then conjugated to the GM to preferentially target oral squamous cancer (KB) cells with folate receptors expressed on their membranes and facilitate the transit of the nanoparticles across the cell membrane. Finally, a fluorescence dye (Atto) was conjugated to the nanoparticles to visualize their internalization into KB cells. After culture of the cells in a medium containing GM and folate-conjugated GM (GF), the interaction of surface-modified gold nanoparticles with KB cells was studied.

Indexed as

Folic acidGold nanoparticlesIntracellular uptakeKB cells

Identifiers

PMID25852305
PMCPMC4311903
OpenAlexW2131692626

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.